Discovery and mechanism of ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders

JM Benson, D Peritt, BJ Scallon, GA Heavner… - MAbs, 2011 - Taylor & Francis
Monoclonal antibody (mAb) therapy was first established upon the approval of a mouse
antibody for treatment of human acute organ rejection. However, the high incidence of …

Psoriasis and suicidality: A systematic review and meta-analysis

S Singh, C Taylor, H Kornmehl… - Journal of the American …, 2017 - Elsevier
Background Psoriasis is associated with psychiatric comorbidities; however, the relationship
between psoriasis and suicidality is not well understood. Objective To perform a systematic …

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

TH Do, F Ma, PR Andrade, R Teles… - Science …, 2022 - science.org
Acne affects 1 in 10 people globally, often resulting in disfigurement. The disease involves
excess production of lipids, particularly squalene, increased growth of Cutibacterium acnes …

[HTML][HTML] Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study

JA Halvorsen, RS Stern, F Dalgard, M Thoresen… - Journal of Investigative …, 2011 - Elsevier
We performed a cross-sectional, questionnaire-based study to explore the relationship of
suicidal ideation, mental health problems, and social functioning to acne severity among …

The psychosocial impact of acne vulgaris

N Hazarika, M Archana - Indian journal of dermatology, 2016 - journals.lww.com
Background: Acne vulgaris causes erythematous papulopustular lesions in active stage and
often leave behind residual scarring and pigmentation. Its onset in adolescence may add to …

Psychiatric comorbidity in chronic urticaria patients: a systematic review and meta-analysis

GN Konstantinou, GN Konstantinou - Clinical and Translational Allergy, 2019 - Springer
Background Dermatological illness can affect the quality of life and may coexist with
psychiatric disorders. Objective The aim of this review was to systematically evaluate the …

The psychosocial and occupational impact of chronic skin disease

J Hong, B Koo, J Koo - Dermatologic therapy, 2008 - Wiley Online Library
Chronic skin diseases, particularly psoriasis and atopic dermatitis, have a negative impact
on patients' quality of life. Patients often experience significant psychological and social …

Understanding the impact of acne vulgaris and associated psychological distress on self-esteem and quality of life via regression modeling with CADI, DLQI, and …

ASM Morshed, T Noor, MA Uddin Ahmed, FS Mili… - Scientific Reports, 2023 - nature.com
Acne vulgaris (AV) is a psychosomatic disorder and can negatively affect individuals,
especially in terms of psychological well-being, self-esteem, and quality of life (QoL). The …

[HTML][HTML] How acne bumps cause the blues: the influence of acne vulgaris on self-esteem

SM Gallitano, DS Berson - International journal of women's dermatology, 2018 - Elsevier
Acne vulgaris is one of the most common dermatologic complaints. Although dermatologists
are skilled at treating acne, invisible psychological scars can be left by the disease. We …

Psychodermatological aspects of atopic dermatitis

MS Senra, A Wollenberg - British journal of dermatology, 2014 - academic.oup.com
Psychodermatology is an evolving area of science that focuses on the interaction between
the mind, skin and body. It is known that various neuroendocrine mediators–including …