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The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
Viral persistence, reactivation, and mechanisms of long COVID
The COVID-19 global pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
Infectious disease in an era of global change
The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not
least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …
least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods …
Lateral flow test engineering and lessons learned from COVID-19
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …
and spreading globally, including in populations with high vaccination rates. We aimed to …
Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …
Prevalence of persistent SARS-CoV-2 in a large community surveillance study
Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future
outbreaks,,,–, give rise to highly divergent lineages,–and contribute to cases with post-acute …
outbreaks,,,–, give rise to highly divergent lineages,–and contribute to cases with post-acute …
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …