Lumbar disc herniation (LDH) can be spontaneously absorbed without surgical treatment.
However, the pathogenesis and physiological indications for predicting protrusion …

The purpose of this review was to evaluate data generated by animal models of
intervertebral disc (IVD) degeneration published in the last decade and show how this has …

Intervertebral disk (IVD) degeneration is a natural progression of the aging process.
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …

Musculoskeletal disorders represent a major cause of disability and morbidity globally and
result in enormous costs for health and social care systems. Development of cell-based …

Intervertebral disc (IVD) degeneration is frequently associated with low back and neck pain,
which accounts for disability worldwide. Despite the known outcomes of the IVD …

Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a
problem with a heavy economic burden, which has been increasing in prevalence as …

Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to
intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is …

Strategies for the biological repair of intervertebral discs derive from the premise that disc
degeneration results from impaired cellular activity and, therefore, that these structures can …

Degeneration of the intervertebral discs, a process characterized by a cascade of cellular,
biochemical, structural and functional changes, is strongly implicated as a cause of low back …

The intervertebral disc (IVD) is a moderately moving joint that is located between the bony
vertebrae and provides flexibility and load transmission throughout the spinal column. The …