Epigenetic regulation in lung cancer

S Ramazi, M Dadzadi, Z Sahafnejad, A Allahverdi - MedComm, 2023 - Wiley Online Library
Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …

An overview of the epigenetic modifications in the brain under normal and pathological conditions

L Lossi, C Castagna, A Merighi - International Journal of Molecular …, 2024 - mdpi.com
Epigenetic changes are changes in gene expression that do not involve alterations to the
DNA sequence. These changes lead to establishing a so-called epigenetic code that …

Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line

S Ramazi, M Salimian, A Allahverdi, S Kianamiri… - Scientific Reports, 2023 - nature.com
Breast cancer is one of the leading causes of cancer deaths in women worldwide. Magnetic
fields have shown anti-tumor effects in vitro and in vivo as a non-invasive therapy method …

An updated patent review of BRD4 degraders

Z Ma, C Zhang, AA Bolinger, J Zhou - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Bromodomain-containing protein 4 (BRD4), an important epigenetic reader, is
closely associated with the pathogenesis and development of many diseases, including …

Gastric cancer in the era of epigenetics

G Christodoulidis, KE Koumarelas, MN Kouliou… - International Journal of …, 2024 - mdpi.com
Gastric cancer (GC) remains a significant contributor to cancer-related mortality. Novel high-
throughput techniques have enlightened the epigenetic mechanisms governing gene …

An overview of advances in rare cancer diagnosis and treatment

G Christyani, M Carswell, S Qin, W Kim - International Journal of …, 2024 - mdpi.com
Cancer stands as the leading global cause of mortality, with rare cancer comprising 230
distinct subtypes characterized by infrequent incidence. Despite the inherent challenges in …

[HTML][HTML] Epidermal growth factor receptor tyrosine kinase inhibitors in cancer: Current use and future prospects

H Dickerson, A Diab, O Al Musaimi - International Journal of Molecular …, 2024 - mdpi.com
Tyrosine kinase inhibitors (TKIs) have emerged as a leading targeted cancer therapy,
reducing the side effects often seen with non-targeted treatments, especially the damage to …

[HTML][HTML] Microrna-mediated regulation of histone-modifying enzymes in cancer: mechanisms and therapeutic implications

J Szczepanek, A Tretyn - Biomolecules, 2023 - mdpi.com
In the past decade, significant advances in molecular research have provided a deeper
understanding of the intricate regulatory mechanisms involved in carcinogenesis …

Heavy metals toxicity on epigenetic modifications in the pathogenesis of Alzheimer's disease (AD)

D Venkatesan, S Muthukumar, M Iyer… - … of biochemical and …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a progressive decline in cognitive ability and behavior which
eventually disrupts daily activities. AD has no cure and the progression rate varies unlikely …

Beyond genetics: can micro and nanoplastics induce epigenetic and gene-expression modifications?

AMG Poma, P Morciano, M Aloisi - Frontiers in Epigenetics and …, 2023 - frontiersin.org
Plastic pollution is becoming a worldwide crisis. It can be found in all environmental
matrices, from the seas to the oceans, from dry land to the air we breathe. Because of the …