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[HTML][HTML] Multimodal experimental studies of the passive mechanical behavior of human aortas: Current approaches and future directions
Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
[HTML][HTML] Why are viscosity and nonlinearity bound to make an impact in clinical elastographic diagnosis?
The adoption of multiscale approaches by the biomechanical community has caused a
major improvement in quality in the mechanical characterization of soft tissues. The recent …
major improvement in quality in the mechanical characterization of soft tissues. The recent …
[HTML][HTML] Multiscale computational modeling of arterial micromechanics: A review
M Dalbosco, EA Fancello, GA Holzapfel - Computer Methods in Applied …, 2024 - Elsevier
The mechanical properties of arterial tissue play a central role in healthy human physiology
and have therefore been extensively studied and modeled in recent decades. These …
and have therefore been extensively studied and modeled in recent decades. These …
Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers
The extracellular matrix (ECM) plays an active and dynamic role that both reflects and
facilitates the functional requirements of a tissue. The mature ECM of the nonpregnant cervix …
facilitates the functional requirements of a tissue. The mature ECM of the nonpregnant cervix …
[HTML][HTML] Changes in the microstructure of the human aortic adventitia under biaxial loading investigated by multi-photon microscopy
A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2023 - Elsevier
Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …
mechanical properties, but the adventitia prevents the aorta from overstretching and …
Mechanics of cervical remodelling: insights from rodent models of pregnancy
The uterine cervix undergoes a complex remodelling process during pregnancy,
characterized by dramatic changes in both extracellular matrix (ECM) structure and …
characterized by dramatic changes in both extracellular matrix (ECM) structure and …
Differences in collagen fiber diameter and waviness between healthy and aneurysmal abdominal aortas
Collagen plays a key role in the strength of aortic walls, so studying micro-structural changes
during disease development is critical to better understand collagen reorganization. Second …
during disease development is critical to better understand collagen reorganization. Second …
[HTML][HTML] Changes in the microstructure of the human aortic medial layer under biaxial loading investigated by multi-photon microscopy
A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2022 - Elsevier
Understanding the correlation between tissue architecture, health status, and mechanical
properties is essential for improving material models and develo** tissue engineering …
properties is essential for improving material models and develo** tissue engineering …
Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection
This study analyzes the lethal clinical condition of aortic dissections from a numerical point
of view. On the basis of previous contributions by Gültekin et al.(Comput Methods Appl Mech …
of view. On the basis of previous contributions by Gültekin et al.(Comput Methods Appl Mech …
Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy
A bstract The cervix undergoes rapid and dramatic shifts in collagen and elastic fiber
structure to achieve its disparate physiological roles of competence during pregnancy and …
structure to achieve its disparate physiological roles of competence during pregnancy and …