Acute lymphoblastic leukemia is the most common blood cancer in pediatric patients. There
has been enormous progress in ALL treatment in recent years, which is reflected by the …

PURPOSE Total body irradiation (TBI) before allogeneic hematopoietic stem cell
transplantation (HSCT) in pediatric patients with acute lymphoblastic leukemia (ALL) is …

Allogeneic hematopoietic stem cell transplantation (HSCT) offers potentially curative
treatment for many children with high-risk or relapsed acute leukemia (AL), thanks to the …

COI notes: DWL has consulted for Harpoon Therapeutics, has advised for Amgen and BMS,
and has research funding from Kite Pharma and Gilead. SAG has research funding from …

Simple Summary Despite very poor survival, controversies remain in the treatment for
refractory or relapsed non-Hodgkin lymphoma (r/r NHL) in children and adolescents. The …

ABSTRACT HLA-haploidentical transplantation (haplo-HCT) using post-transplantation-
cyclophosphamide (PT-Cy) is a feasible procedure in children with malignancies. However …

Minor Histocompatibility (H) antigens are major histocompatibility complex (MHC)/Human
Leukocyte Antigen (HLA)-bound peptides that differ between allogeneic hematopoietic stem …

Chimeric antigen receptor T-cell therapy (CAR-T) targeting CD19 has been associated with
remarkable responses in paediatric patients and adolescents and young adults (AYA) with …

Total body irradiation (TBI) has been a pivotal component of the conditioning regimen for
allogeneic myeloablative haematopoietic stem cell transplantation (HSCT) in very-high-risk …

Immune reconstitution (IR) after allogeneic haematopoietic cell transplantation (HCT)
represents a central determinant of the clinical post-transplant course, since the majority of …