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Iron imbalance in neurodegeneration
Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …
anomalies in its distribution and concentration in brain tissue have been found to be …
Neurodegeneration with brain iron accumulation
SJ Hayflick, MA Kurian, P Hogarth - Handbook of clinical neurology, 2018 - Elsevier
Neurodegeneration with brain iron accumulation (NBIA) comprises a clinically and
genetically heterogeneous group of disorders affecting children and adults. These rare …
genetically heterogeneous group of disorders affecting children and adults. These rare …
Oxidative stress and neurodegeneration: the involvement of iron
A Carocci, A Catalano, MS Sinicropi, G Genchi - Biometals, 2018 - Springer
Many evidences indicate that oxidative stress plays a significant role in a variety of human
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
Neurodegeneration with brain iron accumulation: diagnosis and management
P Hogarth - Journal of movement disorders, 2015 - pmc.ncbi.nlm.nih.gov
Neurodegeneration with brain iron accumulation (NBIA) encompasses a group of inherited
disorders that share the clinical features of an extrapyramidal movement disorder …
disorders that share the clinical features of an extrapyramidal movement disorder …
New perspectives in iron chelation therapy for the treatment of neurodegenerative diseases
Iron chelation has been introduced as a new therapeutic concept for the treatment of
neurodegenerative diseases with features of iron overload. At difference with iron chelators …
neurodegenerative diseases with features of iron overload. At difference with iron chelators …
Regulation of coenzyme A levels by degradation: the 'Ins and Outs'
Coenzyme A (CoA) is the predominant acyl carrier in mammalian cells and a cofactor that
plays a key role in energy and lipid metabolism. CoA and its thioesters (acyl-CoAs) regulate …
plays a key role in energy and lipid metabolism. CoA and its thioesters (acyl-CoAs) regulate …