Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …
limited understanding of its clinical pathogenic spectrum of infection and disease …
[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …
encompassing nine members of closely related species that causes tuberculosis in animals …
Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers
Tuberculosis is the leading infectious cause of death worldwide, with 9· 6 million cases and
1· 5 million deaths reported in 2014. WHO estimates 480 000 cases of these were multidrug …
1· 5 million deaths reported in 2014. WHO estimates 480 000 cases of these were multidrug …
Circulating microRNAs as potential biomarkers of infectious disease
CN Correia, NC Nalpas, KE McLoughlin… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that
regulate a wide range of biological processes by post-transcriptionally regulating gene …
regulate a wide range of biological processes by post-transcriptionally regulating gene …
Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms
Motivation Analysis of gene set (GS) enrichment is an essential part of functional omics
studies. Here, we complement the established evaluation metrics of GS enrichment …
studies. Here, we complement the established evaluation metrics of GS enrichment …
Tuberculosis biomarkers: from diagnosis to protection
New approaches to control tuberculosis (TB) worldwide are needed. In particular, new tools
for diagnosis and new biomarkers are required to evaluate both pathogen and host key …
for diagnosis and new biomarkers are required to evaluate both pathogen and host key …
[HTML][HTML] Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis
DJ Garay-Baquero, CH White, NF Walker… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Tuberculosis (TB) kills more people than any other infection, and new
diagnostic tests to identify active cases are required. We aimed to discover and verify novel …
diagnostic tests to identify active cases are required. We aimed to discover and verify novel …
Next-generation sequencing based HLA ty**: deciphering immunogenetic aspects of sarcoidosis
A Kishore, M Petrek - Frontiers in genetics, 2018 - frontiersin.org
Unraveling of the HLA-related immunogenetic basis of several immune disorders is complex
due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA …
due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA …
From simple to complex: Protein‐based biomarker discovery in tuberculosis
Tuberculosis (TB) is a deadly infectious disease that affects millions of people globally. TB
proteomics signature discovery has been a rapidly growing area of research that aims to …
proteomics signature discovery has been a rapidly growing area of research that aims to …
Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis
M Wang, W Kong, B He, Z Li, H Song, P Shi, J Wang - Clinical Epigenetics, 2018 - Springer
Background A variety of abnormalities in vitamin D metabolism have been reported in
patients with active tuberculosis. However, intervention trials have produced inconsistent …
patients with active tuberculosis. However, intervention trials have produced inconsistent …