Treatment of non-infectious corneal injury: review of diagnostic agents, therapeutic medications, and future targets

DH Dang, KM Riaz, D Karamichos - Drugs, 2022 - Springer
Corneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic,
autoimmune, and iatrogenic causes. Ocular infection may frequently occur concurrent to …

Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis

RB Singh, S Das, J Chodosh, N Sharma… - Progress in Retinal and …, 2022 - Elsevier
Bacterial keratitis continues to be one of the leading causes of corneal blindness in the
developed as well as the develo** world, despite swift progress since the dawn of the …

Super-cationic carbon quantum dots synthesized from spermidine as an eye drop formulation for topical treatment of bacterial keratitis

HJ Jian, RS Wu, TY Lin, YJ Li, HJ Lin, SG Harroun… - ACS …, 2017 - ACS Publications
We have developed a one-step method to synthesize carbon quantum dots (CQDPAs) from
biogenic polyamines (PAs) as an antibacterial agent for topical treatment of bacterial …

Carbonized nanogels for simultaneous antibacterial and antioxidant treatment of bacterial keratitis

HY Lin, SW Wang, JY Mao, HT Chang… - Chemical Engineering …, 2021 - Elsevier
To prevent visual loss, clinical therapy of severe bacterial keratitis (BK) demands
simultaneous remedying of the damage caused by bacterial infection and its induced …

Corticosteroids for bacterial keratitis: the Steroids for Corneal Ulcers Trial (SCUT)

M Srinivasan, J Mascarenhas… - Archives of …, 2012 - jamanetwork.com
Objective To determine whether there is a benefit in clinical outcomes with the use of topical
corticosteroids as adjunctive therapy in the treatment of bacterial corneal ulcers. Methods …

Development of besifloxacin HCl loaded nanofibrous ocular inserts for the treatment of bacterial keratitis: In vitro, ex vivo and in vivo evaluation

HK Polat, SB Pehlivan, C Özkul, S Çalamak… - International journal of …, 2020 - Elsevier
Novel drug delivery systems have emerged to treat bacterial keratitis, an acute infection of
the cornea. In this study, besifloxacin HCl loaded insert formulations were designed and …

Review of contact lens–related complications

CHL Lim, F Stapleton, JS Mehta - Eye & contact lens, 2018 - journals.lww.com
The purpose of this article is to provide a review of existing literature describing
complications with contemporary contact lenses and their management. It is envisioned that …

Tailoring therapeutic properties of silver nanoparticles for effective bacterial keratitis treatment

DD Nguyen, SJ Lue, JY Lai - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
The formulation of nanoparticles with intrinsically therapeutic properties in a tailorable and
appropriate manner is critical in nanomedicine for effective treatments of infectious diseases …

Toward understanding the purely geometric effects of silver nanoparticles on potential application as ocular therapeutics via treatment of bacterial keratitis

DD Nguyen, LJ Luo, JY Lai - Materials Science and Engineering: C, 2021 - Elsevier
Understanding a complex interaction between therapeutic nanoparticles and biological
entities is crucially important for the development of effective disease treatments in the …

Advanced bioengineering strategies broaden the therapeutic landscape for corneal failure

R Al Monla, V Daien, F Michon - Frontiers in Bioengineering and …, 2024 - frontiersin.org
The cornea acts as the eye foremost protective layer and is essential for its focusing power.
Corneal blindness may arise from physical trauma or conditions like dystrophies, keratitis …