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[HTML][HTML] The nicotinamide/streptozotocin rodent model of type 2 diabetes: renal pathophysiology and redox imbalance features
LJ Yan - Biomolecules, 2022 - mdpi.com
Diabetic nephropathy (DN) is a common complication of diabetes mellitus. While there has
been a great advance in our understanding of the pathogenesis of DN, no effective …
been a great advance in our understanding of the pathogenesis of DN, no effective …
Anthocyanins and vascular health: a matter of metabolites
Anthocyanins are a subgroup of flavonoid polyphenols previously investigated for improving
cardiovascular health and preventing the development of endothelial dysfunction. However …
cardiovascular health and preventing the development of endothelial dysfunction. However …
[HTML][HTML] Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis
J Ni, L Zhang, G Feng, W Bao, Y Wang, Y Huang… - Pharmacological …, 2024 - Elsevier
The damage of integrated epithelial epithelium is a key pathogenic factor and closely
associated with the recurrence of ulcerative colitis (UC). Here, we reported that vanillic acid …
associated with the recurrence of ulcerative colitis (UC). Here, we reported that vanillic acid …
Metabolomics profiling distinctively identified end-stage renal disease patients from chronic kidney disease patients
LA Dahabiyeh, RM Nimer, KM Sumaily… - Scientific Reports, 2023 - nature.com
Chronic kidney disease (CKD) is a serious public health problem characterized by
progressive kidney function loss leading to end-stage renal disease (ESRD) that demands …
progressive kidney function loss leading to end-stage renal disease (ESRD) that demands …
Phytochemical profiling, toxicity studies, wound healing, analgesic and anti-inflammatory activities of Musa paradisiaca L. Musaceae (Plantain) stem extract in rats
CN Ekweogu, EI Akubugwo, O Emmanuel… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance The stem of Musa paradisiaca (plantain) has found
application in traditional medicine for the treatment of diabetes, inflammation, ulcers and …
application in traditional medicine for the treatment of diabetes, inflammation, ulcers and …
Emerging roles and therapeutic applications of Arachidonic Acid pathways in Cardiometabolic diseases
Cardiometabolic disease has become a major health burden worldwide, with sharply
increasing prevalence but highly limited therapeutic interventions. Emerging evidence has …
increasing prevalence but highly limited therapeutic interventions. Emerging evidence has …
Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes‐associated cognitive decline: An in vivo study in a rat model
Hippocampal synaptic dysfunction, oxidative stress, neuroinflammation, and neuronal loss
play critical roles in the pathophysiology of diabetes‐associated cognitive decline (DACD) …
play critical roles in the pathophysiology of diabetes‐associated cognitive decline (DACD) …
Determination of Chemical Composition and Investigation of Biological Activities of Ocimum basilicum L.
This study aimed to determine the chemical composition of the essential oils (EOs) of
Ocimum basilicum L., as well as to evaluate the antibacterial, antidiabetic …
Ocimum basilicum L., as well as to evaluate the antibacterial, antidiabetic …
[HTML][HTML] Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional …
GY Choi, IS Lee, E Moon, H Choi, AR Je… - Biomedicine & …, 2024 - Elsevier
Alzheimer's disease (AD) is characterized by cognitive impairment, loss of learning and
memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of …
memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of …
Gentisic acid protects against diabetic nephropathy in Nicotinamide-Streptozotocin administered male mice by attenuating oxidative stress and inflammation: The role …
Oxidative stress and inflammation play a pivotal role in the pathogenesis of diabetic
nephropathy (DN). Local renin-angiotensin systems (RAS) contribute to the pathogenesis …
nephropathy (DN). Local renin-angiotensin systems (RAS) contribute to the pathogenesis …