Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases
Abstract Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with
over 100 known substrates to deal with. How does GSK3 maintain control to selectively …
over 100 known substrates to deal with. How does GSK3 maintain control to selectively …
GSK3: a kinase balancing promotion and resolution of inflammation
L Hoffmeister, M Diekmann, K Brand, R Huber - Cells, 2020 - mdpi.com
GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …
plethora of scientific reports using a variety of experimental (disease) models and …
[PDF][PDF] DDX17‐regulated alternative splicing that produced an oncogenic isoform of PXN‐AS1 to promote HCC metastasis
HZ Zhou, F Li, ST Cheng, Y Xu, HJ Deng, DY Gu… - …, 2022 - Wiley Online Library
Abstract Background and Aims The mechanism underlying HCC metastasis remains
unclear, many oncogenes are known to regulate this process. However, the role of …
unclear, many oncogenes are known to regulate this process. However, the role of …
RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation
The RNA helicases DDX5 and DDX17 are members of a large family of highly conserved
proteins that are involved in gene-expression regulation; however, their in vivo targets and …
proteins that are involved in gene-expression regulation; however, their in vivo targets and …
The RNA splicing response to DNA damage
The number of factors known to participate in the DNA damage response (DDR) has
expanded considerably in recent years to include splicing and alternative splicing factors …
expanded considerably in recent years to include splicing and alternative splicing factors …
DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
K Xu, S Sun, M Yan, J Cui, Y Yang, W Li… - Frontiers in …, 2022 - frontiersin.org
DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense
DEAD-box helicases play essential roles in RNA metabolism across species, but emerging
data suggest that they have additional functions in immunity. Through RNAi screening, we …
data suggest that they have additional functions in immunity. Through RNAi screening, we …
Roles of DDX5 in the tumorigenesis, proliferation, differentiation, metastasis and pathway regulation of human malignancies
RM Nyamao, J Wu, L Yu, X **ao, FM Zhang - Biochimica et Biophysica Acta …, 2019 - Elsevier
The DEAD-box RNA helicase DDX5 is a member of a family of highly conserved proteins
involved in gene-expression regulation and ATP-dependent RNA helicase activities …
involved in gene-expression regulation and ATP-dependent RNA helicase activities …
The role of DEAD‐box RNA helicase p68 (DDX5) in the development and treatment of breast cancer
V Hashemi, A Masjedi, B Hazhir‐karzar… - Journal of cellular …, 2019 - Wiley Online Library
RNA helicase p68 or DEAD (Asp‐Glu‐Ala‐Asp) box polypeptide 5 (DDX5) is a unique
member of the highly conserved protein family, which is involved in a broad spectrum of …
member of the highly conserved protein family, which is involved in a broad spectrum of …
[HTML][HTML] Functions of DEAD box RNA helicases DDX5 and DDX17 in chromatin organization and transcriptional regulation
G Giraud, S Terrone, CF Bourgeois - BMB reports, 2018 - ncbi.nlm.nih.gov
Abstract RNA helicases DDX5 and DDX17 are multitasking proteins that regulate gene
expression in different biological contexts through diverse activities. Special attention has …
expression in different biological contexts through diverse activities. Special attention has …