Over the last decade, deep learning (DL) methods have been extremely successful and
widely used to develop artificial intelligence (AI) in almost every domain, especially after it …

With the dramatic development of high-performance computing, the emergence of better
algorithms and the accumulation of large amounts of chemical and biological data, computer …

Therapeutic antibodies targeting PD-1 have made major breakthroughs in cancer treatment.
However, the majority of colorectal cancer (CRC) cases are microsatellite stable (MSS) and …

The present work adopted a systems pharmacology-based approach to provide new
insights into the active compounds and therapeutic targets of Bufei Yishen formula (BYF) for …

The rapidly increasing diabetes mellitus (DM) is becoming a major global public health
issue. Traditional Chinese medicine (TCM) has a long history of the treatment of DM with …

Target identification of the known bioactive compounds and novel synthetic analogs is a
very important research field in medicinal chemistry, biochemistry, and pharmacology. It is …

Abstract Herb pair Danggui-Honghua has been frequently used for treatment of blood stasis
syndrome (BSS) in China, one of the most common clinical pathological syndromes in …

Ethnopharmacology relevance The main therapeutic concept in Traditional Chinese
Medicine (TCM) is herb formula, which treats various diseases via potential herb interactions …

Artificial intelligence (AI) renders cutting-edge applications in diverse sectors of society. Due
to substantial progress in high-performance computing, the development of superior …

Colorectal cancer remains the third leading cause of cancer death worldwide, suggesting
exploration of novel therapeutic avenues may be useful. In this study, therefore, we …