Cyanide is a nitrile which is used extensively in many industries like jewelry, mining,
electroplating, plastics, dyes, paints, pharmaceuticals, food processing, and coal coking …

The cyanide-degrading nitrilases are of notable interest for their potential to remediate
cyanide contaminated waste streams, especially as generated in the gold mining …

The cyanide-containing effluents originate from, eg, mining, coking, electroplating and
chemical syntheses. The form and concentration of cyanide, and the effluent matrix depend …

Searching for new and better biocatalysts is an area of study in constant development. In
nature, mechanisms generally occurring in evolution, such as genetic duplication …

Free cyanide (fCN) consisting of HCN and CN-is highly hazardous. Today, removal of
cyanide from industrial (mining, plating, coke-plant) wastewaters largely relies on …

The thermostability of nitrilase from different microorganisms varies widely and is closely
related to conserved sequences. In this study, a semi-rational design based on sequence …

Nitrilases are helical enzymes that convert nitriles to acids and/or amides. All plants have a
nitrilase 4 homolog specific for ß-cyanoalanine, while in some plants neofunctionalization …

Cyanide degrading nitrilases are noted for their potential to detoxify industrial wastewater
contaminated with cyanide. However, such application would benefit from an improvement …

Understanding the biochemistry and metabolic pathways of cyanide degradation is
necessary to improve the efficacy of cyanide bioremediation processes and industrial …

Cyanide is toxic to most living organisms. The toxicity of cyanide derives from its ability to
inhibit the enzyme cytochrome C oxidase of the electronic transport chain. Despite its high …