Background and aims Many patients with liver disease come to medical attention once they
have advanced cirrhosis or acute decompensation. Most often, patients are screened for …

Emerging evidence shows that Metastasis-associated lung adenocarcinoma transcript 1
(MALAT1) plays a pivotal role in cell proliferation, migration, and invasion in tumors …

Degenerative diseases are marked by continuous and progressive deterioration of the
function of cells which is not caused by any underlying trauma or infection. The economic …

Hepatic stellate cell (HSC) activation is considered as a central driver of liver fibrosis and
effective suppression of HSC activation contributes to the treatment of liver fibrosis. Circular …

TGF-β1 is a major player in chronic liver diseases promoting fibrogenesis and tumorigenesis
through various mechanisms. The expression and function of TGF-β2 have not been …

Liver fibrosis is a common public health problem. Patients with liver fibrosis are more likely
to develop cirrhosis, or hepatocellular carcinoma (HCC) as a more serious consequence …

Metabolic dysfunction-associated fatty liver disease (MAFLD) encompasses a spectrum of
liver diseases ranging from metabolic dysfunction-associated fatty liver to metabolic …

Liver fibrosis/cirrhosis is a pathological state caused by excessive extracellular matrix
deposition. Sustained activation of hepatic stellate cells (HSC) is the predominant cause of …

Hepatic fibrosis is the common end stage to a variety of chronic liver injuries and is
characterized by an excessive deposition of extracellular matrix (ECM), which disrupts the …

Ovarian cancer is the most common type of gynecological malignant tumor, with the highest
mortality rate among female genital malignant tumors. In this study, we initially identified …