An introduction to TRP channels
▪ Abstract The aim of this review is to provide a basic framework for understanding the
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
TRP channels: an overview
The TRP (“transient receptor potential”) family of ion channels now comprises more than 30
cation channels, most of which are permeable for Ca2+, and some also for Mg2+. On the …
cation channels, most of which are permeable for Ca2+, and some also for Mg2+. On the …
Regulation of endothelial permeability via paracellular and transcellular transport pathways
Y Komarova, AB Malik - Annual review of physiology, 2010 - annualreviews.org
The endothelium functions as a semipermeable barrier regulating tissue fluid homeostasis
and transmigration of leukocytes and providing essential nutrients across the vessel wall …
and transmigration of leukocytes and providing essential nutrients across the vessel wall …
Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling
EW Bush, DB Hood, PJ Papst, JA Chapo… - Journal of Biological …, 2006 - ASBMB
The calcium/calmodulin-dependent phosphatase calcineurin plays a central role in the
control of cardiomyocyte hypertrophy in response to pathological stimuli. Although …
control of cardiomyocyte hypertrophy in response to pathological stimuli. Although …
Phospholipase C signaling and calcium influx
JW Putney, T Tomita - Advances in biological regulation, 2012 - Elsevier
Calcium signaling is a process whereby the extremely low cytoplasmic Ca2+ concentration
increases in a deliberate and specific manner to trigger downstream cellular events. Virtually …
increases in a deliberate and specific manner to trigger downstream cellular events. Virtually …
Ca2+ Signaling, TRP Channels, and Endothelial Permeability
Increased endothelial permeability is the hallmark of inflammatory vascular edema.
Inflammatory mediators that bind to heptahelical G protein-coupled receptors trigger …
Inflammatory mediators that bind to heptahelical G protein-coupled receptors trigger …
Recent developments in vascular endothelial cell transient receptor potential channels
Among the 28 identified and unique mammalian TRP (transient receptor potential) channel
isoforms, at least 19 are expressed in vascular endothelial cells. These channels appear to …
isoforms, at least 19 are expressed in vascular endothelial cells. These channels appear to …
TRP channels
M Gees, G Owsianik, B Nilius… - Comprehensive …, 2011 - Wiley Online Library
TRP channels constitute a large superfamily of cation channel forming proteins, all related to
the gene product of the transient receptor potential (trp) locus in Drosophila. In mammals, 28 …
the gene product of the transient receptor potential (trp) locus in Drosophila. In mammals, 28 …
TRPC channels function independently of STIM1 and Orai1
WI DeHaven, B Jones, J Petranka, T Tomita, J Putney - Biophysical Journal, 2009 - cell.com
Peter J. Calcraft1, Abdelilah Arredouani2, Zui Pan3, **aotong Cheng2, Jisen Tang4,
Margarida Ruas2, Katja Rietdorf2, Peihui Lin3, John Parrington2, Jianjie Ma3, A. Mark …
Margarida Ruas2, Katja Rietdorf2, Peihui Lin3, John Parrington2, Jianjie Ma3, A. Mark …
New insights on mast cell activation via the high affinity receptor for IgE
J Rivera, NA Fierro, A Olivera, R Suzuki - Advances in immunology, 2008 - Elsevier
Mast cells are innate immune cells that function as regulatory or effector cells and serve to
amplify adaptive immunity. In adaptive immunity these cells function primarily through cell …
amplify adaptive immunity. In adaptive immunity these cells function primarily through cell …