Synergistic brilliance: engineered bacteria and nanomedicine unite in cancer therapy

Y Zhou, Q Li, Y Wu, W Zhang, L Ding, C Ji… - Advanced …, 2024 - Wiley Online Library
Engineered bacteria are widely used in cancer treatment because live facultative/obligate
anaerobes can selectively proliferate at tumor sites and reach hypoxic regions, thereby …

Nanomaterials‐Induced Redox Imbalance: Challenged and Opportunities for Nanomaterials in Cancer Therapy

X Wu, Z Zhou, K Li, S Liu - Advanced Science, 2024 - Wiley Online Library
Cancer cells typically display redox imbalance compared with normal cells due to increased
metabolic rate, accumulated mitochondrial dysfunction, elevated cell signaling, and …

Redox‐Active Ferrocene Quencher‐Based Supramolecular Nanomedicine for NIR‐II Fluorescence‐Monitored Chemodynamic Therapy

M Yu, Z Ye, S Liu, Y Zhu, X Niu, J Wang… - Angewandte …, 2024 - Wiley Online Library
Real‐time monitoring of hydroxyl radical (⋅ OH) generation is crucial for both the efficacy
and safety of chemodynamic therapy (CDT). Although⋅ OH probe‐integrated CDT agents …

A Polymeric Nanoparticle to Co‐Deliver Mitochondria‐Targeting Peptides and Pt (IV) Prodrug: Toward High Loading Efficiency and Combination Efficacy

J Yang, Z Yang, H Wang, Y Chang… - Angewandte Chemie …, 2024 - Wiley Online Library
Develo** combination chemotherapy systems with high drug loading efficiency at
predetermined drug ratios to achieve a synergistic effect is important for cancer therapy …

A mesoporous superparamagnetic iron oxide nanoparticle as a generic drug delivery system for tumor ferroptosis therapy

J Yang, W **ong, L Huang, Z Li, Q Fan, F Hu… - Journal of …, 2024 - Springer
As a famous drug delivery system (DDS), mesoporous organosilica nanoparticles (MON) are
degraded slowly in vivo and the degraded components are not useful for cell nutrition or …

Covalent organic frameworks-derived carbon nanospheres based nanoplatform for tumor specific synergistic therapy via oxidative stress amplification and calcium …

Y Pang, J Lv, C He, C Ju, Y Lin, C Zhang… - Journal of colloid and …, 2024 - Elsevier
Combinational therapy in cancer treatment that integrates the merits of different therapies is
an effective approach to improve therapeutic outcomes. Herein, a simple nanoplatform (N …

Carrier-free nanodrugs: from bench to bedside

F Fang, X Chen - ACS nano, 2024 - ACS Publications
Carrier-free nanodrugs with extraordinary active pharmaceutical ingredient (API) loading
(even 100%), avoidable carrier-induced toxicity, and simple synthetic procedures are …

Cyclic catalysis of intratumor Fe3+/2+ initiated by a hollow mesoporous iron sesquioxide nanoparticle for ferroptosis therapy of large tumors

J Yang, B Ren, H Cai, W **ong, J Feng, Q Fan, Z Li… - Biomaterials, 2025 - Elsevier
Numerous nanoparticles have been utilized to deliver Fe 2+ for tumor ferroptosis therapy,
which can be readily converted to Fe 3+ via Fenton reactions to generate hydroxyl radical (• …

Tumor acidification and GSH depletion by bimetallic composite nanoparticles for enhanced chemodynamic therapy of TNBC

W Chen, F Hu, Q Gao, C Zheng, Q Bai, J Liu… - Journal of …, 2024 - Springer
Chemodynamic therapy (CDT) based on intracellular Fenton reaction to produce highly
cytotoxic reactive oxygen species (ROS) has played an essential role in tumor therapy …

Bimetallic DNAsome Decorated with G4‐DNA as a Nanozyme for Targeted and Enhanced Chemo/Chemodynamic Cancer Therapy

G Raj, AP Vasantha, VD Sreekumar… - Advanced …, 2024 - Wiley Online Library
Cancer is indisputably one of the major threats to mankind, and hence the design of new
approaches for the improvement of existing therapeutic strategies is always wanted. Herein …