Role of microbial communities in the pathogenesis of periodontal diseases and caries

A Mira, A Simon‐Soro, MA Curtis - Journal of clinical …, 2017 - Wiley Online Library
The microbiological characteristics of both caries and periodontal disease show significant
change from those in health. In both instances, there is evidence of co‐association of …

Mixed red‐complex bacterial infection in periodontitis

N Suzuki, M Yoneda, T Hirofuji - International journal of …, 2013 - Wiley Online Library
The red complex, which includes Porphyromonas gingivalis, Treponema denticola, and
Tannerella forsythia (formerly Bacteroides forsythus), are recognized as the most important …

Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis

IM Velsko, SS Chukkapalli, MF Rivera, JY Lee, H Chen… - PloS one, 2014 - journals.plos.org
Atherosclerotic vascular disease is a leading cause of myocardial infarction and
cerebrovascular accident, and independent associations with periodontal disease (PD) are …

Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis

JI Aguirre, MP Akhter, DB Kimmel… - Journal of Bone and …, 2012 - academic.oup.com
Though osteonecrosis of the jaw (ONJ) is temporally‐associated with the use of nitrogen‐
containing bisphosphonates (N‐BPs), a cause‐and‐effect relationship has not yet been …

Polymicrobial Oral Infection with Four Periodontal Bacteria Orchestrates a Distinct Inflammatory Response and Atherosclerosis in ApoEnull Mice

SS Chukkapalli, IM Velsko, MF Rivera-Kweh, D Zheng… - PloS one, 2015 - journals.plos.org
Periodontal disease (PD) develops from a synergy of complex subgingival oral microbiome,
and is linked to systemic inflammatory atherosclerotic vascular disease (ASVD). To …

Polymicrobial Infection with Major Periodontal Pathogens Induced Periodontal Disease and Aortic Atherosclerosis in Hyperlipidemic ApoEnull Mice

MF Rivera, JY Lee, M Aneja, V Goswami, L Liu… - PloS one, 2013 - journals.plos.org
Periodontal disease (PD) and atherosclerosis are both polymicrobial and multifactorial and
although observational studies supported the association, the causative relationship …

Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers

SS Chukkapalli, MF Rivera-Kweh… - Pathogens and …, 2015 - academic.oup.com
Tannerella forsythia is a Gram-negative anaerobic organism that inhabits the subgingival
cavity and initiates connective tissue destruction and alveolar bone resorption in periodontal …

Synergistic virulence of Porphyromonas gingivalis and Treponema denticola in a murine periodontitis model

RKH Orth, NM O'Brien‐Simpson… - Molecular oral …, 2011 - Wiley Online Library
Chronic periodontitis is characterized by the destruction of the tissues supporting the teeth
and has been associated with the presence of a subgingival polymicrobial biofilm containing …

Development of a root canal treatment model in the rat

N Yoneda, Y Noiri, S Matsui, K Kuremoto, H Maezono… - Scientific reports, 2017 - nature.com
Root canal treatment is performed to treat apical periodontitis, and various procedures and
techniques are currently used. Although animal models have been used in the …

Increased Atherogenesis during Streptococcus mutans Infection in ApoE-null Mice

L Kesavalu, AR Lucas, RK Verma… - Journal of Dental …, 2012 - journals.sagepub.com
Streptococcus mutans, a dental caries pathogen, also causes endocarditis and is detected
in atheroscelerotic plaque. We investigated the potential for an invasive strain of S. mutans …