Macrophages are critical regulators of tissue homeostasis but are also abundant in the
tumor microenvironment (TME). In both primary tumors and metastases, such tumor …

Forty years after its naming, interleukin-1 (IL-1) is experiencing a renaissance brought on by
the growing understanding of its context-dependent roles and advances in the clinic. Recent …

Inflammation is an important component of the tumor microenvironment. IL‐1 is an
inflammatory cytokine which plays a key role in carcinogenesis and tumor progression. IL‐1 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

The response of the body to a cancer is not a unique mechanism but has many parallels
with inflammation and wound healing. This article reviews the links between cancer and …

Abstract Micro (nano)-plastics (MP/NPs) ubiquity in the environment constitutes the global
environmental and toxicological related issues of the 21st century. MP/NPs are now …

Endothelial cells play a wide variety of critical roles in the control of vascular function.
Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure …

An analysis of published data appertaining to the cytokine storms of COVID-19, H1N1
influenza, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS) …

Abstract IL-6−/− mice showed impaired leukocyte accumulation in subcutaneous air
pouches. Defective leukocyte accumulation was not due to a reduced migratory capacity of …

Type II (non-insulin-dependent) diabetes mellitus is associated with increased blood
concentrations of markers of the acute-phase response, including sialic acid, α-1 acid …