Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …

Chemotherapy is the primary established systemic treatment for patients with triple-negative
breast cancer (TNBC) in both the early and advanced-stages of the disease. The lack of …

Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …

Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …

Abstract Rationale: Cancer stem cells (CSCs) are considered to be essential for
tumorigenesis, recurrence, and metastasis and therefore serve as a biomarker for tumor …

Abstract The EGFR/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway plays prominent roles in
malignant transformation, prevention of apoptosis, drug resistance and metastasis. The …

Breast cancer is the most frequent cancer among women worldwide. Therapeutic strategies
to prevent or treat metastatic disease are still inadequate although great progress has been …

Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …

Oxaliplatin (OXA), is a third generation platinum drug used as first‐line chemotherapy in
colorectal cancer (CRC). Cancer cells acquires resistance to anti‐cancer drug and develops …