BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Activatable molecular probes for fluorescence-guided surgery, endoscopy and tissue biopsy

Y Zhang, G Zhang, Z Zeng, K Pu - Chemical Society Reviews, 2022 - pubs.rsc.org
The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

Visible-light-mediated modification and manipulation of biomacromolecules

VM Lechner, M Nappi, PJ Deneny, S Folliet… - Chemical …, 2021 - ACS Publications
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …

The design and bioimaging applications of NIR fluorescent organic dyes with high brightness

J Wu, Z Shi, L Zhu, J Li, X Han, M Xu… - Advanced Optical …, 2022 - Wiley Online Library
Due to the merits of decreased photon attenuation, autofluorescence, and scattering, the
near‐infrared (NIR, 700–1700 nm) region is an important window in the field of biomedicine …

Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

V Almeida-Marrero, E van de Winckel… - Chemical Society …, 2018 - pubs.rsc.org
The development of photoactive and biocompatible nanomaterials is a current major
challenge of materials science and nanotechnology, as they will contribute to promoting …

Fluorescent amino acids as versatile building blocks for chemical biology

Z Cheng, E Kuru, A Sachdeva, M Vendrell - Nature Reviews Chemistry, 2020 - nature.com
Fluorophores have transformed the way we study biological systems, enabling non-invasive
studies in cells and intact organisms, which increase our understanding of complex …

Small Fluorogenic Amino Acids for Peptide‐Guided Background‐Free Imaging

F De Moliner, Z Konieczna… - Angewandte Chemie …, 2023 - Wiley Online Library
The multiple applications of super‐resolution microscopy have prompted the need for
minimally invasive labeling strategies for peptide‐guided fluorescence imaging. Many …

Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes

N Kaplaneris, J Son, L Mendive-Tapia, A Kopp… - Nature …, 2021 - nature.com
Bioorthogonal late-stage diversification of amino acids and peptides bears enormous
potential for drug discovery and molecular imaging. Despite major accomplishments, these …

Recent progress in the development of singlet oxygen carriers for enhanced photodynamic therapy

G Li, M Wu, Y Xu, Q Wang, J Liu, X Zhou, H Ji… - Coordination Chemistry …, 2023 - Elsevier
Hypoxia is a significant feature of the tumor, which has been proved to be the major
challenge in translating photodynamic therapy (PDT) into clinical applications. To solve this …

SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism

S Benson, A Fernandez, ND Barth… - Angewandte …, 2019 - Wiley Online Library
The transport and trafficking of metabolites are critical for the correct functioning of live cells.
However, in situ metabolic imaging studies are hampered by the lack of fluorescent …