Transposable elements are endogenous DNA sequences able to integrate into and multiply
within genomes. They constitute a major source of genetic innovations, as they can not only …

Constitutive heterochromatin represents a significant portion of eukaryotic genomes, but its
functions still need to be elucidated. Even in the most updated genetics and molecular …

Heterochromatic repeat-rich regions are often missing from even the best genome
assemblies. Chang and Larracuente designed a de novo assembly strategy to improve the …

The rapid evolution of repetitive DNA sequences, including satellite DNA, tandem
duplications, and transposable elements, underlies phenotypic evolution and contributes to …

Small noncoding piRNAs act as sequence-specific guides to repress complementary targets
in Metazoa. Prior studies in Drosophila ovaries have demonstrated the function of the piRNA …

Y chromosomes control essential male functions in many species, including sex
determination and fertility. However, because of obstacles posed by repeat-rich …

Highly repetitive satellite DNA (satDNA) repeats are found in most eukaryotic genomes.
SatDNAs are rapidly evolving and have roles in genome stability and chromosome …

Y chromosomes across diverse species convergently evolve a gene-poor, heterochromatic
organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA …

Eukaryotic gene regulation is a complex process, often coordinated by the action of tens to
hundreds of proteins. Although previous biochemical studies have identified many …

Loss of recombination between sex chromosomes often depletes Y chromosomes of
functional content and genetic variation, which might limit their potential to generate …