Subunit vaccines against emerging pathogenic human coronaviruses
Seven coronaviruses (CoVs) have been isolated from humans so far. Among them, three
emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus …
emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus …
The effects of type 2 diabetes mellitus on organ metabolism and the immune system
Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and
obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM) …
obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM) …
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
H Gu, Q Chen, G Yang, L He, H Fan, YQ Deng, Y Wang… - Science, 2020 - science.org
The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the
development of small-animal models for severe acute respiratory syndrome coronavirus 2 …
development of small-animal models for severe acute respiratory syndrome coronavirus 2 …
[HTML][HTML] Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor …
Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) has posed a serious threat
to global public health, calling for the development of safe and effective prophylactics and …
to global public health, calling for the development of safe and effective prophylactics and …
From SARS to MERS, thrusting coronaviruses into the spotlight
Z Song, Y Xu, L Bao, L Zhang, P Yu, Y Qu, H Zhu… - viruses, 2019 - mdpi.com
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
[HTML][HTML] Origin and evolution of pathogenic coronaviruses
J Cui, F Li, ZL Shi - Nature reviews microbiology, 2019 - nature.com
Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory
syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses …
syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses …
Overview of lethal human coronaviruses
B Chen, EK Tian, B He, L Tian, R Han… - Signal transduction and …, 2020 - nature.com
Coronavirus infections of multiple origins have spread to date worldwide, causing severe
respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV …
respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV …
Coronaviruses—drug discovery and therapeutic options
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …
challenges to public health security and the global economy. The development and …
Structure, function, and evolution of coronavirus spike proteins
F Li - Annual review of virology, 2016 - annualreviews.org
The coronavirus spike protein is a multifunctional molecular machine that mediates
coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its …
coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its …