The integrated brain network that controls respiration

F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Emerging connections between cerebellar development, behaviour and complex brain disorders

A Sathyanesan, J Zhou, J Scafidi, DH Heck… - Nature Reviews …, 2019 - nature.com
The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

The connectome of the adult Drosophila mushroom body provides insights into function

F Li, JW Lindsey, EC Marin, N Otto, M Dreher… - Elife, 2020 - elifesciences.org
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

Cerebellar granule cells encode the expectation of reward

MJ Wagner, TH Kim, J Savall, MJ Schnitzer, L Luo - Nature, 2017 - nature.com
The human brain contains approximately 60 billion cerebellar granule cells, which
outnumber all other brain neurons combined. Classical theories posit that a large, diverse …

The cerebellum, sensitive periods, and autism

SSH Wang, AD Kloth, A Badura - Neuron, 2014 - cell.com
Cerebellar research has focused principally on adult motor function. However, the
cerebellum also maintains abundant connections with nonmotor brain regions throughout …

The cerebellar cortex

C Hull, WG Regehr - Annual review of neuroscience, 2022 - annualreviews.org
The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Optimal degrees of synaptic connectivity

A Litwin-Kumar, KD Harris, R Axel, H Sompolinsky… - Neuron, 2017 - cell.com
Synaptic connectivity varies widely across neuronal types. Cerebellar granule cells receive
five orders of magnitude fewer inputs than the Purkinje cells they innervate, and cerebellum …

Re-evaluating circuit mechanisms underlying pattern separation

NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlap** patterns of activity that represent sensory and motor information. Pattern …

[HTML][HTML] Reward signals in the cerebellum: origins, targets, and functional implications

D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …

Computational principles of supervised learning in the cerebellum

JL Raymond, JF Medina - Annual review of neuroscience, 2018 - annualreviews.org
Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …