Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases

G Wigerblad, MJ Kaplan - Nature Reviews Immunology, 2023 - nature.com
Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …

Patients with COVID-19: in the dark-NETs of neutrophils

M Ackermann, HJ Anders, R Bilyy, GL Bowlin… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

The role of neutrophil extracellular traps in acute lung injury

D Scozzi, F Liao, AS Krupnick, D Kreisel… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

[HTML][HTML] Myeloperoxidase: regulation of neutrophil function and target for therapy

SA Rizo-Téllez, M Sekheri, JG Filep - Antioxidants, 2022 - mdpi.com
Neutrophils, the most abundant white blood cells in humans, are critical for host defense
against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils …

Roles of neutrophil granule proteins in orchestrating inflammation and immunity

A Othman, M Sekheri, JG Filep - The FEBS journal, 2022 - Wiley Online Library
Neutrophil granulocytes form the first line of host defense against invading pathogens and
tissue injury. They are rapidly recruited from the blood to the affected sites, where they …

Biological roles of neutrophil-derived granule proteins and cytokines

MA Cassatella, NK Östberg, N Tamassia… - Trends in …, 2019 - cell.com
Neutrophils, the most abundant white blood cells in human circulation, entertain intense
interactions with other leukocyte subsets, platelets, and stromal cells. Molecularly, such …

Asymptomatic hyperuricaemia: a silent activator of the innate immune system

LAB Joosten, TO Crişan, P Bjornstad… - Nature Reviews …, 2020 - nature.com
Asymptomatic hyperuricaemia affects~ 20% of the general population in the USA, with
variable rates in other countries. Historically, asymptomatic hyperuricaemia was considered …

[HTML][HTML] Role of neutrophils in cardiac injury and repair following myocardial infarction

Y Ma - Cells, 2021 - mdpi.com
Neutrophils are first-line responders of the innate immune system. Following myocardial
infarction (MI), neutrophils are quickly recruited to the ischemic region, where they initiate …

How glucocorticoids affect the neutrophil life

S Ronchetti, E Ricci, G Migliorati, M Gentili… - International journal of …, 2018 - mdpi.com
Glucocorticoids are hormones that regulate several functions in living organisms and
synthetic glucocorticoids are the most powerful anti-inflammatory pharmacological tool that …