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The rise and current status of polaritonic photochemistry and photophysics
The interaction between molecular electronic transitions and electromagnetic fields can be
enlarged to the point where distinct hybrid light–matter states, polaritons, emerge. The …
enlarged to the point where distinct hybrid light–matter states, polaritons, emerge. The …
Optical tweezers in single-molecule biophysics
Optical tweezers have become the method of choice in single-molecule manipulation
studies. In this Primer, we first review the physical principles of optical tweezers and the …
studies. In this Primer, we first review the physical principles of optical tweezers and the …
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …
Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region
INTRODUCTION A mechanistic understanding of brain function requires the identification of
distinct cell types in the brain at a molecular, spatial, and functional level. The preoptic …
distinct cell types in the brain at a molecular, spatial, and functional level. The preoptic …
Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells
INTRODUCTION Chromatin adopts an intricate three-dimensional (3D) organization in the
nucleus that is critical for many genome processes, from gene regulation to genome …
nucleus that is critical for many genome processes, from gene regulation to genome …
Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics
The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …
Extreme disorder in an ultrahigh-affinity protein complex
Molecular communication in biology is mediated by protein interactions. According to the
current paradigm, the specificity and affinity required for these interactions are encoded in …
current paradigm, the specificity and affinity required for these interactions are encoded in …
Super-resolution microscopy with DNA-PAINT
Super-resolution techniques have begun to transform biological and biomedical research by
allowing researchers to observe structures well below the classic diffraction limit of light …
allowing researchers to observe structures well below the classic diffraction limit of light …
Single particle tracking: from theory to biophysical applications
After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …
Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT
Super-resolution fluorescence microscopy is a powerful tool for biological research, but
obtaining multiplexed images for a large number of distinct target species remains …
obtaining multiplexed images for a large number of distinct target species remains …