The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

[HTML][HTML] Inflammaging: implications in sarcopenia

E Antuña, C Cachán-Vega, JC Bermejo-Millo… - International journal of …, 2022 - mdpi.com
In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …

Electrospun fiber‐based immune engineering in regenerative medicine

Y Xu, Q Saiding, X Zhou, J Wang, W Cui… - Smart Medicine, 2024 - Wiley Online Library
Immune engineering, a burgeoning field within regenerative medicine, involves a spectrum
of strategies to optimize the intricate interplay between tissue regenerative biomaterials and …

New insights into pathomechanisms and treatment possibilities for lung silicosis

J Adamcakova, D Mokra - International journal of molecular sciences, 2021 - mdpi.com
Inhalation of silica particles is an environmental and occupational cause of silicosis, a type
of pneumoconiosis. Development of the lung silicosis is a unique process in which the …

Enhanced diabetic wound healing using platelet-derived extracellular vesicles and reduced graphene oxide in polymer-coordinated hydrogels

PC Hao, T Burnouf, CW Chiang, PR Jheng… - Journal of …, 2023 - Springer
Impaired wound healing is a significant complication of diabetes. Platelet-derived
extracellular vesicles (pEVs), rich in growth factors and cytokines, show promise as a …

Hues of risk: investigating genotoxicity and environmental impacts of azo textile dyes

K Ramamurthy, PS Priya, R Murugan… - … Science and Pollution …, 2024 - Springer
The textile industry, with its extensive use of dyes and chemicals, stands out as a significant
source of water pollution. Exposure to certain textile dyes, such as azo dyes and their …

Macrophage plasticity: signaling pathways, tissue repair, and regeneration

L Yan, J Wang, X Cai, YC Liou, HM Shen, J Hao… - MedComm, 2024 - Wiley Online Library
Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt
to diverse tissue microenvironments and perform various functions. Traditionally categorized …

Intestinal fibrosis in inflammatory bowel disease and the prospects of mesenchymal stem cell therapy

Y Wang, B Huang, T **, DKW Ocansey… - Frontiers in …, 2022 - frontiersin.org
Intestinal fibrosis is an important complication of inflammatory bowel disease (IBD). In the
course of the development of fibrosis, certain parts of the intestine become narrowed …

The emerging roles of interstitial macrophages in pulmonary fibrosis: a perspective from scRNA-seq analyses

Y Gu, T Lawrence, R Mohamed, Y Liang… - Frontiers in …, 2022 - frontiersin.org
Pulmonary fibrosis is an irreversible and progressive disease affecting the lungs, and the
etiology remains poorly understood. This disease can be lethal and currently has no specific …