Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

Oxidative stress, an imbalance between reactive oxygen species and antioxidants, has been
seen in the pathological states of many disorders such as ischemic diseases and cancers …

Targeting aberrant metabolism is a promising strategy for inhibiting cancer growth and
metastasis. Research is now geared towards investigating the inhibition of glycolysis for …

Betulinic acid (BA), as a prospective natural compound, shows outstanding antitumor
bioactivities against many solid malignancies. However, its mechanism against multiple …

Natural products serve as the single most productive source for the discovery of drugs and
pharmaceutical leads. Among the various chemicals derived from microbes, plants, and …

Although previous studies have shown anti-cancer activity of betulinic acid (BA), a
pentacyclic triterpenoid, against various cancer lines, the underlying molecular mechanisms …

Cervical cancer is considered to be one of the most serious malignant tumors in women.
Natural compounds have been considered as important sources in the search for new …

Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid and generally found in the
bark of birch trees (Betula sp.). Although several studies have been reported that BA has …

Herein, a derivate from tanshinone IIA, 1, 6, 6-trimethyl-11-phenyl-7, 8, 9, 10-tetrahydro-6H-
furo [2′, 3′: 1, 2] phenanthro [3, 4-d] imidazole (TA25), has been synthesized and …

Cervical cancer is the fourth most common female malignancy with high morbidity and
mortality, which urgently needs novel anti-cancer drugs. Accumulating investigations have …