Multi-omics data integration, interpretation, and its application

I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …

Multi-omic and multi-view clustering algorithms: review and cancer benchmark

N Rappoport, R Shamir - Nucleic acids research, 2018 - academic.oup.com
Recent high throughput experimental methods have been used to collect large biomedical
omics datasets. Clustering of single omic datasets has proven invaluable for biological and …

Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019 - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

Unsupervised multi-omics data integration methods: a comprehensive review

N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …

Methods for the integration of multi-omics data: mathematical aspects

M Bersanelli, E Mosca, D Remondini, E Giampieri… - BMC …, 2016 - Springer
Background Methods for the integrative analysis of multi-omics data are required to draw a
more complete and accurate picture of the dynamics of molecular systems. The complexity …

Statistical analysis of high-dimensional biomedical data: a gentle introduction to analytical goals, common approaches and challenges

J Rahnenführer, R De Bin, A Benner, F Ambrogi… - BMC medicine, 2023 - Springer
Background In high-dimensional data (HDD) settings, the number of variables associated
with each observation is very large. Prominent examples of HDD in biomedical research …

Evaluation and comparison of multi-omics data integration methods for cancer subty**

R Duan, L Gao, Y Gao, Y Hu, H Xu… - PLoS computational …, 2021 - journals.plos.org
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subty** have …

[HTML][HTML] Approaches to integrating metabolomics and multi-omics data: a primer

T Jendoubi - Metabolites, 2021 - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Bayesian consensus clustering

EF Lock, DB Dunson - Bioinformatics, 2013 - academic.oup.com
Motivation: In biomedical research a growing number of platforms and technologies are
used to measure diverse but related information, and the task of clustering a set of objects …

Bayesian correlated clustering to integrate multiple datasets

P Kirk, JE Griffin, RS Savage, Z Ghahramani… - …, 2012 - academic.oup.com
Motivation: The integration of multiple datasets remains a key challenge in systems biology
and genomic medicine. Modern high-throughput technologies generate a broad array of …