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A primer to directed evolution: current methodologies and future directions
Directed evolution is one of the most powerful tools for protein engineering and functions by
harnessing natural evolution, but on a shorter timescale. It enables the rapid selection of …
harnessing natural evolution, but on a shorter timescale. It enables the rapid selection of …
Genome size diversity and its impact on the evolution of land plants
Genome size is a biodiversity trait that shows staggering diversity across eukaryotes, varying
over 64,000-fold. Of all major taxonomic groups, land plants stand out due to their …
over 64,000-fold. Of all major taxonomic groups, land plants stand out due to their …
From molecules to populations: appreciating and estimating recombination rate variation
Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …
Using haplotype information for conservation genomics
The particular combinations of alleles that define haplotypes along individual chromosomes
can be determined with increasing ease and accuracy by using current sequencing …
can be determined with increasing ease and accuracy by using current sequencing …
Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery
LM Mollé, CH Smyth, D Yuen… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nucleic acid therapeutics can be used to control virtually every aspect of cell behavior and
therefore have significant potential to treat genetic disorders, infectious diseases, and …
therefore have significant potential to treat genetic disorders, infectious diseases, and …
Locally adaptive inversions modulate genetic variation at different geographic scales in a seaweed fly
Across a species range, multiple sources of environmental heterogeneity, at both small and
large scales, create complex landscapes of selection, which may challenge adaptation …
large scales, create complex landscapes of selection, which may challenge adaptation …
Environmental adaptation of genetically uniform organisms with the help of epigenetic mechanisms—An insightful perspective on ecoepigenetics
G Vogt - Epigenomes, 2022 - mdpi.com
Organisms adapt to different environments by selection of the most suitable phenotypes from
the standing genetic variation or by phenotypic plasticity, the ability of single genotypes to …
the standing genetic variation or by phenotypic plasticity, the ability of single genotypes to …
Genomic features of parthenogenetic animals
Evolution without sex is predicted to impact genomes in numerous ways. Case studies of
individual parthenogenetic animals have reported peculiar genomic features that were …
individual parthenogenetic animals have reported peculiar genomic features that were …
Practical considerations will ensure the continued success of pre-harvest biocontrol using non-aflatoxigenic Aspergillus flavus strains
GG Moore - Critical Reviews in Food Science and Nutrition, 2022 - Taylor & Francis
There is an important reason for the accelerated use of non-aflatoxigenic Aspergillus flavus
to mitigate pre-harvest aflatoxin contamination… it effectively addresses the imperative need …
to mitigate pre-harvest aflatoxin contamination… it effectively addresses the imperative need …
Per-nucleus crossover covariation and implications for evolution
Crossing over is a nearly universal feature of sexual reproduction. Here, analysis of
crossover numbers on a per-chromosome and per-nucleus basis reveals a fundamental …
crossover numbers on a per-chromosome and per-nucleus basis reveals a fundamental …