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Lyme disease pathogenesis
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
Complement control protein factor H: the good, the bad, and the inadequate
The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …
participates in elimination of pathogens and altered host cells and comprises an essential …
Host association of Borrelia burgdorferi sensu lato–the key role of host complement
K Kurtenbach, S De Michelis, S Etti, SM Schäfer… - Trends in …, 2002 - cell.com
Borrelia burgdorferi sensu lato (sl), the tick-borne agent of Lyme borreliosis, is a bacterial
species complex comprising 11 genospecies. Here, we discuss whether the delineation of …
species complex comprising 11 genospecies. Here, we discuss whether the delineation of …
Intravascular immunity: the host–pathogen encounter in blood vessels
The immune system provides an essential defence against invading pathogens. However,
bacteria have evolved numerous strategies to overcome this defence, many of which …
bacteria have evolved numerous strategies to overcome this defence, many of which …
Hijacking factor H for complement immune evasion
The complement system is an essential player in innate and adaptive immunity. It consists of
three pathways (alternative, classical, and lectin) that initiate either spontaneously …
three pathways (alternative, classical, and lectin) that initiate either spontaneously …
Ecology of Borrelia burgdorferi sensu lato in Europe: transmission dynamics in multi-host systems, influence of molecular processes and effects of climate change
The analysis of different multi-host systems suggests that even hosts that are not capable of
transmitting Borrelia burgdorferi sensu lato (sl.) to the tick vector, Ixodes ricinus, or that are …
transmitting Borrelia burgdorferi sensu lato (sl.) to the tick vector, Ixodes ricinus, or that are …
Plasminogen is a complement inhibitor
Plasminogen is a 92-kDa single chain glycoprotein that circulates in plasma as a zymogen
and when converted to proteolytically active plasmin dissolves preformed fibrin clots and …
and when converted to proteolytically active plasmin dissolves preformed fibrin clots and …
Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein
Pseudomonas aeruginosa is an opportunistic human pathogen that can cause a wide range
of clinical symptoms and infections that are frequent in immunocompromised patients. In this …
of clinical symptoms and infections that are frequent in immunocompromised patients. In this …
[HTML][HTML] Regulation of regulators: Role of the complement factor H-related proteins
The complement system, while being an essential and very efficient effector component of
innate immunity, may cause damage to the host and result in various inflammatory …
innate immunity, may cause damage to the host and result in various inflammatory …
Outer membrane proteins of pathogenic spirochetes
Pathogenic spirochetes are the causative agents of several important diseases including
syphilis, Lyme disease, leptospirosis, swine dysentery, periodontal disease and some forms …
syphilis, Lyme disease, leptospirosis, swine dysentery, periodontal disease and some forms …