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Critical periods of vulnerability for the develo** nervous system: evidence from humans and animal models.
D Rice, S Barone Jr - Environmental health perspectives, 2000 - ehp.niehs.nih.gov
Vulnerable periods during the development of the nervous system are sensitive to
environmental insults because they are dependent on the temporal and regional emergence …
environmental insults because they are dependent on the temporal and regional emergence …
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment
This review examines the large body of toxicological and epidemiological information on
human exposures to chlorpyrifos, with an emphasis on the controversial potential for …
human exposures to chlorpyrifos, with an emphasis on the controversial potential for …
Exposures of children to organophosphate pesticides and their potential adverse health effects.
B Eskenazi, A Bradman… - Environmental health …, 1999 - ehp.niehs.nih.gov
Recent studies show that young children can be exposed to pesticides during normal oral
exploration of their environment and their level of dermal contact with floors and other …
exploration of their environment and their level of dermal contact with floors and other …
Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children
OBJECTIVE. The purpose of this study was to investigate the impact of prenatal exposure to
chlorpyrifos on 3-year neurodevelopment and behavior in a sample of inner-city minority …
chlorpyrifos on 3-year neurodevelopment and behavior in a sample of inner-city minority …
Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates
Acetylcholine and other neurotransmitters play unique trophic roles in brain development.
Accordingly, drugs and environmental toxicants that promote or interfere with …
Accordingly, drugs and environmental toxicants that promote or interfere with …
Developmental neurotoxicity of succeeding generations of insecticides
Insecticides are by design toxic. They must be toxic to effectively kill target species of insects.
Unfortunately, they also have off-target toxic effects that can harm other species, including …
Unfortunately, they also have off-target toxic effects that can harm other species, including …
NMR‐based metabonomic approaches for evaluating physiological influences on biofluid composition
Strategies such as genomics, proteomics and metabonomics are being applied with
increasing frequency in the pharmaceutical industry. For each of these approaches …
increasing frequency in the pharmaceutical industry. For each of these approaches …
Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations
Use of chlorpyrifos (CPF) has been curtailed due to its developmental neurotoxicity. In rats,
postnatal CPF administration produces lasting changes in cognitive performance, but less …
postnatal CPF administration produces lasting changes in cognitive performance, but less …
Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats
Chlorpyrifos (CPF) is a widely used insecticides which has been shown to alter brain cell
development. The current project was conducted to determine whether there are persistent …
development. The current project was conducted to determine whether there are persistent …
Differential sensitivity of children and adults to chemical toxicity: I. Biological basis
Children, particularly neonates, can be biologically more sensitive to the same toxicant
exposure on a body weight basis than adults. Current understanding of the rates of …
exposure on a body weight basis than adults. Current understanding of the rates of …