DEAD-box ATPases constitute a very large protein family present in all cells, often in great
abundance. From bacteria to humans, they play critical roles in many aspects of RNA …

Prion-like low-complexity domains (PLCDs) have distinctive sequence grammars that
determine their driving forces for phase separation. Here we uncover the physicochemical …

RNA-dependent DEAD-box ATPases (DDXs) are emerging as major regulators of RNA-
containing membrane-less organelles (MLOs). On the one hand, oligomerizing DDXs can …

Post‐translational modifications (PTMs) have emerged as key modulators of protein phase
separation and have been linked to protein aggregation in neurodegenerative disorders …

Liquid-liquid phase separation (LLPS) of proteins is thought to be a primary driving force for
the formation of membraneless organelles, which control a wide range of biological …

Liquid-liquid phase separation or LLPS of proteins is a field of mounting importance and the
value of quantitative kinetic and thermodynamic characterization of LLPS is increasingly …

This perspective article highlights recent progress and emerging challenges in
understanding the formation and function of membraneless organelles (MLOs). A long-term …

Reproductive success of metazoans relies on germ cells. These cells develop early during
embryogenesis, divide and undergo meiosis in the adult to make sperm and oocytes. Unlike …

The surface tension of liquid-like protein-rich biomolecular condensates is an emerging
physical principle governing the mesoscopic interior organisation of biological cells. In this …

Eukaryotic cells are composed of different bio-macromolecules that are divided into
compartments called organelles providing optimal microenvironments for many cellular …