Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …
chemotherapeutic drugs have shown considerable potential to reverse the …
Carrier-free nanomedicines for cancer treatment
LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …
Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …
confirmed to activate the host immune system to prevent, control, and eliminate tumors …
Self‐Assembling Peptide‐Based Functional Biomaterials
Peptides can self‐assemble into various hierarchical nanostructures through noncovalent
interactions and form functional materials exhibiting excellent chemical and physical …
interactions and form functional materials exhibiting excellent chemical and physical …
[HTML][HTML] Anti-PD-L1 peptide-conjugated prodrug nanoparticles for targeted cancer immunotherapy combining PD-L1 blockade with immunogenic cell death
Rationale: Cancer immunotherapy combining immune checkpoint blockade (ICB) with
chemotherapeutic drugs has provided significant clinical advances. However, such …
chemotherapeutic drugs has provided significant clinical advances. However, such …
Photothermal “nano-dot” reactivate “immune-hot” for tumor treatment via reprogramming cancer cells metabolism
Y Lu, Y Wang, W Liu, H Ma, B Yang, K Shao, S Long… - Biomaterials, 2023 - Elsevier
Cancer immunotherapy, despite its enormous application prospect, is trapped in the
abnormal lactic acid metabolism of tumor cells that usually causes an immunosuppressive …
abnormal lactic acid metabolism of tumor cells that usually causes an immunosuppressive …
Doxorubicin prodrug-based nanomedicines for the treatment of cancer
H Zhao, J Yu, R Zhang, P Chen, H Jiang… - European journal of …, 2023 - Elsevier
The chemotherapeutic drug of doxorubicin (DOX) has witnessed widespread applications
for treating various cancers. DOX-treated dying cells bear cellular modifications which allow …
for treating various cancers. DOX-treated dying cells bear cellular modifications which allow …
Polymeric STING Pro‐agonists for Tumor‐Specific Sonodynamic Immunotherapy
The efficacy of combination immunotherapy has been limited by tumor specificity and
immune‐related adverse events (irAEs). Herein, we report the development of polymeric …
immune‐related adverse events (irAEs). Herein, we report the development of polymeric …
Recent progress, perspectives, and issues of engineered PD-L1 regulation nano-system to better cure tumor: A review
Z Zhou, H Wang, J Li, X Jiang, Z Li, J Shen - International Journal of …, 2024 - Elsevier
Currently, immune checkpoint blockade (ICB) therapies that target the programmed cell
death ligand-1 (PD-L1) have been used as revolutionary cancer treatments in the clinic …
death ligand-1 (PD-L1) have been used as revolutionary cancer treatments in the clinic …