Hairy root research: recent scenario and exciting prospects

S Guillon, J Tremouillaux-Guiller, PK Pati… - Current opinion in plant …, 2006 - Elsevier
High stability of the production of secondary metabolites is an interesting characteristic of
hairy root cultures. For 25 years, hairy roots have been investigated as a biological system …

Hairy roots: An untapped potential for production of plant products

KJ Morey, CAM Peebles - Frontiers in Plant Science, 2022 - frontiersin.org
While plants are an abundant source of valuable natural products, it is often challenging to
produce those products for commercial application. Often organic synthesis is too expensive …

Hairy root culture technology: applications, constraints and prospect

S Gantait, E Mukherjee - Applied Microbiology and Biotechnology, 2021 - Springer
Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Harnessing the potential of hairy roots: dawn of a new era

S Guillon, J Trémouillaux-Guiller, PK Pati… - TRENDS in …, 2006 - cell.com
In the past two decades, hairy root research for the production of important secondary
metabolites has received a lot of attention. The addition of knowledge to overcome the …

Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila

L Cui, X Ni, Q Ji, X Teng, Y Yang, C Wu, D Zekria… - Scientific Reports, 2015 - nature.com
Camptothecin (CPT) belongs to a group of monoterpenoidindole alkaloids (TIAs) and its
derivatives such as irinothecan and topothecan have been widely used worldwide for the …

Hairy root cultures as a source of phenolic antioxidants: simple phenolics, phenolic acids, phenylethanoids, and hydroxycinnamates

J Malarz, YV Yudina, A Stojakowska - International Journal of Molecular …, 2023 - mdpi.com
Plant-derived antioxidants are intrinsic components of human diet and factors implicated in
tolerance mechanisms against environmental stresses in both plants and humans. They are …

Hairy root culture an alternative for bioactive compound production from medicinal plants

A Roy - Current pharmaceutical biotechnology, 2021 - ingentaconnect.com
Medicinal plants produce a diverse group of phytocompounds like anthraquinones,
alkaloids, anthocyanins, flavonoids, saponins, and terpenes which are used in …

Production of anthraquinones, phenolic compounds and biological activities from hairy root cultures of Polygonum multiflorum Thunb.

M Thiruvengadam, N Praveen, EH Kim, SH Kim… - Protoplasma, 2014 - Springer
Polygonum multiflorum Thunb. is a highly important medicinal plant producing
anthraquinones (emodin and physcion) and phenolic compounds which has pharmaceutical …

Degradation analysis of Reactive Red 198 by hairy roots of Tagetes patula L. (Marigold)

P Patil, N Desai, S Govindwar, JP Jadhav, V Bapat - Planta, 2009 - Springer
Tagetes patula L.(Marigold) hairy roots were selected among few hairy root cultures from
other plants tested for the decolorization of Reactive Red 198. Hairy roots of Tagetes were …

Enhancement of anthraquinone production and release by combination of culture medium selection and methyl jasmonate elicitation in hairy root cultures of Rubia …

M Perassolo, AB Cardillo, ML Mugas… - Industrial Crops and …, 2017 - Elsevier
Anthraquinones (AQs) are secondary metabolites widely distributed in nature. Interesting
applications of plant extracts containing AQs include the treatment of Hepatitis C and cancer …