Organic semiconducting agents for deep‐tissue molecular imaging: second near‐infrared fluorescence, self‐luminescence, and photoacoustics

Q Miao, K Pu - Advanced materials, 2018 - Wiley Online Library
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of
relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering …

Inverse opal scaffolds and their biomedical applications

YS Zhang, C Zhu, Y **a - Advanced Materials, 2017 - Wiley Online Library
Three‐dimensional porous scaffolds play a pivotal role in tissue engineering and
regenerative medicine by functioning as biomimetic substrates to manipulate cellular …

Enhancing both biodegradability and efficacy of semiconducting polymer nanoparticles for photoacoustic imaging and photothermal therapy

Y Lyu, J Zeng, Y Jiang, X Zhen, T Wang, S Qiu, X Lou… - ACS …, 2018 - ACS Publications
Theranostic nanoagents are promising for precision medicine. However, biodegradable
nanoagents with the ability for photoacoustic (PA) imaging guided photothermal therapy …

Intraparticle Molecular Orbital Engineering of Semiconducting Polymer Nanoparticles as Amplified Theranostics for in Vivo Photoacoustic Imaging and Photothermal …

Y Lyu, Y Fang, Q Miao, X Zhen, D Ding, K Pu - ACS nano, 2016 - ACS Publications
Optical theranostic nanoagents that seamlessly and synergistically integrate light-generated
signals with photothermal or photodynamic therapy can provide opportunities for cost …

[HTML][HTML] Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo photoacoustic imaging

K Pu, J Mei, JV Jokerst, G Hong, AL Antaris… - … (Deerfield Beach, Fla …, 2015 - ncbi.nlm.nih.gov
Photoacoustic (PA) imaging is a hybrid and nonionizing imaging technology that integrates
optical excitation with ultrasonic detection based on the PA effect.[1] It provides deeper …

Semiconducting Oligomer Nanoparticles as an Activatable Photoacoustic Probe with Amplified Brightness for In Vivo Imaging of pH.

Q Miao, Y Lyu, D Ding, K Pu - Advanced Materials (Deerfield Beach …, 2016 - europepmc.org
An activatable photoacoustic nanoprobe based on a semiconducting oligomer with
amplified brightness and pH-sensing capability is developed by taking advantage of …

Degradable semiconducting oligomer amphiphile for ratiometric photoacoustic imaging of hypochlorite

C Yin, X Zhen, Q Fan, W Huang, K Pu - Acs Nano, 2017 - ACS Publications
Upregulation of highly reactive oxygen species (ROS) such as hypochlorite (ClO–) is
associated with many pathological conditions including cardiovascular diseases, neuron …

Recent advances of semiconducting polymer nanoparticles in in vivo molecular imaging

K Pu, N Chattopadhyay, J Rao - Journal of Controlled Release, 2016 - Elsevier
Semiconducting polymer nanoparticles (SPNs) emerge as attractive molecular imaging
nanoagents in living animals because of their excellent optical properties including large …

Single cell photoacoustic microscopy: a review

EM Strohm, MJ Moore, MC Kolios - IEEE Journal of Selected …, 2015 - ieeexplore.ieee.org
Photoacoustic imaging has experienced exponential growth over the past decade, with
many applications in biomedicine. One application ideally suited to the analysis of single …

Emerging designs of activatable photoacoustic probes for molecular imaging

Q Miao, K Pu - Bioconjugate chemistry, 2016 - ACS Publications
Photoacoustic (PA) imaging as a new hybrid imaging modality holds great promise for real-
time in vivo monitoring of biological processes with deep tissue penetration and high spatial …