[HTML][HTML] Nucleic acid aptamer-based biosensors: a review

B Sequeira-Antunes, HA Ferreira - Biomedicines, 2023 - mdpi.com
Aptamers, short strands of either DNA, RNA, or peptides, known for their exceptional
specificity and high binding affinity to target molecules, are providing significant …

Phosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition

A George, A Veis - Chemical reviews, 2008 - ACS Publications
Living organisms are capable of inducing the crystallization and deposition of a wide variety
of minerals, 1 but the vertebrates mainly utilize the calcium phosphates in constructing their …

Cancer‐associated fibroblast‐derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib

JW Eun, JH Yoon, HR Ahn, S Kim, YB Kim… - Cancer …, 2023 - Wiley Online Library
Abstract Background Cancer‐associated fibroblasts (CAFs) play an important role in the
induction of chemo‐resistance. This study aimed to clarify the mechanism underlying CAF …

Unique metabolic adaptations dictate distal organ-specific metastatic colonization

T Schild, V Low, J Blenis, AP Gomes - Cancer cell, 2018 - cell.com
Metastases arising from tumors have the proclivity to colonize specific organs, suggesting
that they must rewire their biology to meet the demands of the organ colonized, thus altering …

Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer

A Bellahcène, V Castronovo, KUE Ogbureke… - Nature Reviews …, 2008 - nature.com
Numerous components and pathways are involved in the complex interplay between cancer
cells and their environment. The family of glycophosphoproteins comprising osteopontin …

Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells

CE Allen, L Li, TL Peters, HE Leung, A Yu… - The Journal of …, 2010 - journals.aai.org
Langerhans cell histiocytosis (LCH) is a rare disease characterized by heterogeneous
lesions containing CD207+ Langerhans cells (LCs) and lymphocytes that can arise in …

Hyperpolarized water as universal sensitivity booster in biomolecular NMR

C Hilty, D Kurzbach, L Frydman - Nature protocols, 2022 - nature.com
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

CE Weber, AN Kothari, PY Wai, NY Li, J Driver… - Oncogene, 2015 - nature.com
Interactions between tumor cells and cancer-associated fibroblasts (CAFs) in the tumor
microenvironment significantly influence cancer growth and metastasis. Transforming …

[HTML][HTML] Cellular dormancy in cancer: mechanisms and potential targeting strategies

HY Min, HY Lee - … and Treatment: Official Journal of Korean …, 2023 - synapse.koreamed.org
Cancer is a leading cause of disease-related mortality worldwide. Drug resistance is one of
the primary reasons for the failure of anticancer therapy. There are a number of underlying …

Novel insights into pituitary tumorigenesis: genetic and epigenetic mechanisms

V Srirangam Nadhamuni, M Korbonits - Endocrine reviews, 2020 - academic.oup.com
Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …