Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study)
Background and aims COVID-19 is a dominant pulmonary disease, with multisystem
involvement, depending upon comorbidities. Its profile in patients with pre-existing chronic …
involvement, depending upon comorbidities. Its profile in patients with pre-existing chronic …
APASL clinical practice guideline on hepatitis B reactivation related to the use of immunosuppressive therapy
Abstract Background & Aim Hepatitis B reactivation related to the use of immunosuppressive
therapy remains a major cause of liver-related morbidity and mortality in hepatitis B endemic …
therapy remains a major cause of liver-related morbidity and mortality in hepatitis B endemic …
Portal vein thrombosis in cirrhosis
A Shukla, S Giri - Journal of Clinical and Experimental Hepatology, 2022 - Elsevier
Patients with cirrhosis of the liver are at high risk of develo** portal vein thrombosis (PVT),
which has a complex, multifactorial cause. The condition may present with a myriad of …
which has a complex, multifactorial cause. The condition may present with a myriad of …
Current concepts in coagulation profile in cirrhosis and acute‐on‐chronic liver failure
Background Patients with cirrhosis have profoundly altered hemodynamics and hemostatic
pathways with procoagulant and anticoagulant mechanisms, resulting in a tenuous …
pathways with procoagulant and anticoagulant mechanisms, resulting in a tenuous …
[HTML][HTML] Elevated plasma ICAM1 levels predict 28-day mortality in cirrhotic patients with COVID-19 or bacterial sepsis
Background & Aims Endothelial injury and dysfunction play a detrimental role in the
pathogenesis of infections. Endothelium-related molecules have been reported as potential …
pathogenesis of infections. Endothelium-related molecules have been reported as potential …
Extracellular vesicles as biomarkers in liver disease
R Muñoz-Hernández, Á Rojas, S Gato… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell
types, including hepatocytes, hepatic stellate cells, and immune cells in normal and …
types, including hepatocytes, hepatic stellate cells, and immune cells in normal and …
Are MELD and MELDNa still reliable tools to predict mortality on the liver transplant waiting list?
M Tejedor, N Selzner, M Berenguer - Transplantation, 2022 - journals.lww.com
Liver transplantation is the only curative treatment for end-stage liver disease. Unfortunately,
the scarcity of donor organs and the increasing pool of potential recipients limit access to …
the scarcity of donor organs and the increasing pool of potential recipients limit access to …
Plasma exchange in acute and acute on chronic liver failure
R Maiwall, SK Sarin - Seminars in Liver Disease, 2021 - thieme-connect.com
Liver failure in the context of acute (ALF) and acute on chronic liver failure (ACLF) is
associated with high mortality in the absence of a liver transplant. For decades, therapeutic …
associated with high mortality in the absence of a liver transplant. For decades, therapeutic …
Acute-on-chronic liver failure in cirrhosis
Acute-on-chronic liver failure (ACLF) is a syndrome that develops in patients with acutely
decompensated chronic liver disease. It is characterised by high 28-day mortality, the …
decompensated chronic liver disease. It is characterised by high 28-day mortality, the …
[HTML][HTML] High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure
C Zhou, N Zhang, TT He, Y Wang… - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Patients with hepatitis B virus-associated acute-on-chronic liver failure
(HBV-ACLF) present a complex and poor prognosis. Systemic inflammation plays an …
(HBV-ACLF) present a complex and poor prognosis. Systemic inflammation plays an …