Primary cilia project in a single copy from the surface of most vertebrate cell types; they
detect and transmit extracellular cues to regulate diverse cellular processes during …

Nearly 50 years ago, Chase published a review of hair cycling in which he detailed hair
growth in the mouse and integrated hair biology with the biology of his day. In this review we …

The basal cell nevus syndrome (BCNS) is characterized by developmental abnormalities
and by the postnatal occurrence of cancers, especially basal cell carcinomas (BCCs), the …

Proper regulation of chondrocyte differentiation is necessary for the morphogenesis of
skeletal elements, yet little is known about the molecular regulation of this process. A …

The mechanisms that control cell proliferation and cell differentiation during morphogenesis
of the endochondral skeleton of vertebrates are poorly understood. Indian hedgehog (Ihh) …

A recurrent theme in embryonic development and tissue regeneration is that cells
communicate with each other using just a handful of conserved families of signaling …

During the development of peripheral nerves, neural crest cells generate myelinating and
non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of …

Inappropriate or prolonged inflammation is the main cause of many diseases; for this reason
it is important to understand the physiological mechanisms that terminate inflammation in …

In the mammalian embryo, both sexes are initially morphologically indistinguishable:
specific hormones are required for sex-specific development. Müllerian inhibiting substance …

Cerebellar granule cells are the most abundant type of neuron in the brain, but the
molecular mechanisms that control their generation are incompletely understood. We show …