Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity

A de Morree, TA Rando - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Adult stem cells are important for mammalian tissues, where they act as a cell reserve that
supports normal tissue turnover and can mount a regenerative response following acute …

Control of satellite cell function in muscle regeneration and its disruption in ageing

P Sousa-Victor, L García-Prat… - … Reviews Molecular Cell …, 2022 - nature.com
Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Tissue stem cells: architects of their niches

E Fuchs, HM Blau - Cell stem cell, 2020 - cell.com
Stem cells (SCs) maintain tissue homeostasis and repair wounds. Despite marked variation
in tissue architecture and regenerative demands, SCs often follow similar paradigms in …

Periodontal ligament stem cells: regenerative potency in periodontium

A Tomokiyo, N Wada, H Maeda - Stem cells and development, 2019 - liebertpub.com
Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the
tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and …

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

TJ Sarkar, M Quarta, S Mukherjee, A Colville… - Nature …, 2020 - nature.com
Aging is characterized by a gradual loss of function occurring at the molecular, cellular,
tissue and organismal levels. At the chromatin level, aging associates with progressive …

[HTML][HTML] Production of cultured meat from pig muscle stem cells

H Zhu, Z Wu, X Ding, MJ Post, R Guo, J Wang, J Wu… - Biomaterials, 2022 - Elsevier
Cultured meat is meat for consumption produced in a more sustainable way. It involves cell
harvesting and expansion, differentiation into myotubes, construction into muscle fibres and …

Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing

J Kang, DI Benjamin, S Kim, JS Salvi, G Dhaliwal… - Nature …, 2024 - nature.com
The global loss of heterochromatin during ageing has been observed in eukaryotes from
yeast to humans, and this has been proposed as one of the causes of ageing. However, the …

Stem cells in the treatment of disease

HM Blau, GQ Daley - New England Journal of Medicine, 2019 - Mass Medical Soc
Stem-Cell Research and Clinical Application Stem cells have been the focus of hope, hype,
and a great deal of research. But what exactly is a stem cell, and what are its uses? This …

[HTML][HTML] Therapeutic strategies for Duchenne muscular dystrophy: an update

C Sun, L Shen, Z Zhang, X **e - Genes, 2020 - mdpi.com
Neuromuscular disorders encompass a heterogeneous group of conditions that impair the
function of muscles, motor neurons, peripheral nerves, and neuromuscular junctions. Being …

Orienting muscle stem cells for regeneration in homeostasis, aging, and disease

P Feige, CE Brun, M Ritso, MA Rudnicki - Cell stem cell, 2018 - cell.com
Muscle stem cells, or satellite cells, are required for skeletal muscle maintenance, growth,
and repair. Following satellite cell activation, several factors drive asymmetric cell division to …