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[HTML][HTML] Tryptophan metabolism: a link between the gut microbiota and brain
The gut-brain axis (GBA) is a bilateral communication network between the gastrointestinal
(GI) tract and the central nervous system. The essential amino acid tryptophan contributes to …
(GI) tract and the central nervous system. The essential amino acid tryptophan contributes to …
Gut microbiota regulation of tryptophan metabolism in health and disease
The gut microbiota is a crucial actor in human physiology. Many of these effects are
mediated by metabolites that are either produced by the microbes or derived from the …
mediated by metabolites that are either produced by the microbes or derived from the …
Honeybee gut Lactobacillus modulates host learning and memory behaviors via regulating tryptophan metabolism
Z Zhang, X Mu, Q Cao, Y Shi, X Hu, H Zheng - Nature Communications, 2022 - nature.com
Honeybees are highly social insects with a rich behavioral repertoire and are a versatile
model for neurobiological research. Their gut microbiota comprises a limited number of host …
model for neurobiological research. Their gut microbiota comprises a limited number of host …
Indole-3-propionic acid protects against heart failure with preserved ejection fraction
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a common but
poorly understood form of heart failure, characterized by impaired diastolic function. It is …
poorly understood form of heart failure, characterized by impaired diastolic function. It is …
Hormetic Nutrition and Redox Regulation in Gut–Brain Axis Disorders
M Scuto, F Rampulla, GM Reali, SM Spanò… - Antioxidants, 2024 - mdpi.com
The antioxidant and anti-inflammatory effects of hormetic nutrition for enhancing stress
resilience and overall human health have received much attention. Recently, the gut–brain …
resilience and overall human health have received much attention. Recently, the gut–brain …
[HTML][HTML] Production of indole and indole-related compounds by the intestinal microbiota and consequences for the host: the good, the bad, and the ugly
N Tennoune, M Andriamihaja, F Blachier - Microorganisms, 2022 - mdpi.com
The intestinal microbiota metabolic activity towards the available substrates generates
myriad bacterial metabolites that may accumulate in the luminal fluid. Among them, indole …
myriad bacterial metabolites that may accumulate in the luminal fluid. Among them, indole …
Associations of dietary patterns with brain health from behavioral, neuroimaging, biochemical and genetic analyses
Food preferences significantly influence dietary choices, yet understanding natural dietary
patterns in populations remains limited. Here we identifiy four dietary subtypes by applying …
patterns in populations remains limited. Here we identifiy four dietary subtypes by applying …
Gut dysbiosis in Huntington's disease: associations among gut microbiota, cognitive performance and clinical outcomes
CI Wasser, EC Mercieca, G Kong… - Brain …, 2020 - academic.oup.com
Huntington's disease is characterized by a triad of motor, cognitive and psychiatric
impairments, as well as unintended weight loss. Although much of the research has focused …
impairments, as well as unintended weight loss. Although much of the research has focused …
Systemic tryptophan homeostasis
S Klaessens, V Stroobant, E De Plaen… - Frontiers in molecular …, 2022 - frontiersin.org
Tryptophan is an essential amino acid, which is not only a building block for protein
synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators …
synthesis, but also a precursor for the biosynthesis of co-enzymes and neuromodulators …
Gut‐liver axis‐mediated mechanism of liver cancer: a special focus on the role of gut microbiota
N Ohtani, E Hara - Cancer science, 2021 - Wiley Online Library
Gut microbiota and the mammalian host share a symbiotic relationship, in which the host
provides a suitable ecosystem for the gut bacteria to digest indigestible nutrients and …
provides a suitable ecosystem for the gut bacteria to digest indigestible nutrients and …