Urticaria

P Kolkhir, AM Giménez-Arnau, K Kulthanan… - Nature Reviews …, 2022 - nature.com
Urticaria is an inflammatory skin disorder that affects up to 20% of the world population at
some point during their life. It presents with wheals, angioedema or both due to activation …

The diagnosis and management of acute and chronic urticaria: 2014 update

JA Bernstein, DM Lang, DA Khan, T Craig… - Journal of Allergy and …, 2014 - Elsevier
These parameters were developed by the Joint Task Force on Practice Parameters (JTFPP),
representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the …

Chronic spontaneous urticaria: focus on pathophysiology to unlock treatment advances

A Kaplan, M Lebwohl, AM Giménez‐Arnau, M Hide… - Allergy, 2023 - Wiley Online Library
Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by
intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near …

The pathogenesis of chronic spontaneous urticaria: the role of infiltrating cells

AM Giménez-Arnau, L de Montjoye, R Asero… - The Journal of Allergy …, 2021 - Elsevier
Chronic spontaneous urticaria is characterized by a perivascular non-necrotizing cellular
infiltrate around small venules of the skin. It consists primarily of CD4 (+) lymphocytes, a …

Predictors of treatment response in chronic spontaneous urticaria

JS Fok, P Kolkhir, MK Church, M Maurer - Allergy, 2021 - Wiley Online Library
The current therapeutic algorithm for chronic spontaneous urticaria (CSU), endorsed by the
international guideline, entails treatment escalation from second‐generation H1 …

Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria

AP Kaplan, AM Giménez‐Arnau, SS Saini - Allergy, 2017 - Wiley Online Library
The monoclonal anti‐immunoglobulin E (IgE) antibody, omalizumab, was the first drug
approved for use in patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) who …

Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up

C Antia, K Baquerizo, A Korman, JA Bernstein… - Journal of the American …, 2018 - Elsevier
Urticaria is a common clinical condition presenting with wheals (hives), angioedema, or
both. Urticaria has a complex pathogenesis, along with a high disease burden, a significant …

Urticaria and angioedema: an update on classification and pathogenesis

S Radonjic-Hoesli, KS Hofmeier, S Micaletto… - Clinical reviews in …, 2018 - Springer
Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or
both. In the last years, urticaria has increasingly attracted notice to clinicians and …

Pathogenesis of chronic urticaria

AP Kaplan, M Greaves - Clinical & Experimental Allergy, 2009 - Wiley Online Library
Chronic urticaria is defined as the presence of urticaria (hives) for at least 6 weeks with the
assumption that it occurs daily or close to it. If we eliminate physical urticarias and urticarial …

Predictors of response to omalizumab and relapse in chronic spontaneous urticaria: a study of 470 patients

AV Marzano, G Genovese, G Casazza… - Journal of the …, 2019 - Wiley Online Library
Background Chronic spontaneous urticaria (CSU) is defined as spontaneous occurrence of
wheals and/or angioedema for≥ 6 weeks. Omalizumab is a monoclonal anti‐IgE antibody …