[HTML][HTML] Next-generation sequencing for cancer diagnostics: a practical perspective

C Meldrum, MA Doyle, RW Tothill - The Clinical Biochemist …, 2011 - ncbi.nlm.nih.gov
Next-generation sequencing (NGS) is arguably one of the most significant technological
advances in the biological sciences of the last 30 years. The second generation sequencing …

Cancer of unknown primary site

GR Varadhachary, MN Raber - New England Journal of Medicine, 2014 - Mass Medical Soc
This review summarizes how sophisticated imaging, immunohistochemical testing, and
molecular-profiling tools are changing the approach to cancer of unknown primary site …

Tumor origin detection with tissue-specific miRNA and DNA methylation markers

W Tang, S Wan, Z Yang, AE Teschendorff… - Bioinformatics, 2018 - academic.oup.com
Motivation A clear identification of the primary site of tumor is of great importance to the next
targeted site-specific treatments and could efficiently improve patient's overall survival. Even …

MicroRNAs accurately identify cancer tissue origin

N Rosenfeld, R Aharonov, E Meiri, S Rosenwald… - Nature …, 2008 - nature.com
MicroRNAs (miRNAs) belong to a class of noncoding, regulatory RNAs that is involved in
oncogenesis and shows remarkable tissue specificity. Their potential for tumor classification …

Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010

MS Anglesio, MS Carey, M Köbel, H MacKay… - Gynecologic …, 2011 - Elsevier
OBJECTIVES: Recent literature has highlighted histological types of ovarian carcinoma as
distinct diseases, each with unique clinical and molecular features. Historically, the …

Clear cell carcinoma of the ovary: a review of the literature

MG Del Carmen, M Birrer, JO Schorge - Gynecologic oncology, 2012 - Elsevier
OBJECTIVE: Different histologic types of epithelial ovarian cancer may represent different
diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of …

Significance, detection and markers of disseminated breast cancer cells

M Lacroix - Endocrine-related cancer, 2006 - erc.bioscientifica.com
The development of distant metastases is the major cause of death from breast cancer. In
order to predict and prevent tumour spreading, many attempts are being made to detect …

Endometriosis-associated ovarian cancer: a review of pathogenesis

MJ Worley Jr, WR Welch, RS Berkowitz… - International journal of …, 2013 - mdpi.com
Endometriosis is classically defined as the presence of endometrial glands and stroma
outside of the endometrial lining and uterine musculature. With an estimated frequency of …

Switching benchmarks in cancer of unknown primary: from autopsy to microarray

G Pentheroudakis, V Golfinopoulos… - European journal of cancer, 2007 - Elsevier
INTRODUCTION: Cancer of unknown primary (CUP) is associated with unknown biology
and dismal prognosis. Information on the primary site of origin is scant and has never been …

Model selection approaches for non-linear system identification: a review

X Hong, RJ Mitchell, S Chen, CJ Harris… - … journal of systems …, 2008 - Taylor & Francis
The identification of non-linear systems using only observed finite datasets has become a
mature research area over the last two decades. A class of linear-in-the-parameter models …