COVID-19: Melatonin as a potential adjuvant treatment

R Zhang, X Wang, L Ni, X Di, B Ma, S Niu, C Liu… - Life sciences, 2020 - Elsevier
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …

[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Melatonin has become a popular dietary supplement, most known as a chronobiotic, and for
establishing healthy sleep. Research over the last decade into cancer, Alzheimer's disease …

[HTML][HTML] Is melatonin the cornucopia of the 21st century?

N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment

VMM Giménez, F Inserra, CD Tajer, J Mariani, L Ferder… - Life sciences, 2020 - Elsevier
COVID-19 pandemic has a high mortality rate and is affecting practically the entire world
population. The leading cause of death is severe acute respiratory syndrome as a …

Does evidence exist to blunt inflammatory response by nutraceutical supplementation during COVID-19 pandemic? An overview of systematic reviews of Vitamin D …

S Corrao, R Mallaci Bocchio, M Lo Monaco, G Natoli… - Nutrients, 2021 - mdpi.com
More than one year has passed since the first cases of coronavirus disease 2019 (COVID-
19) caused by severe acute respiratory syndrome (SARS)-CoV-2 coronavirus were reported …

Melatonin in energy control: Circadian time‐giver and homeostatic monitor

E Challet, P Pévet - Journal of Pineal Research, 2024 - Wiley Online Library
Melatonin is a neurohormone synthesized from dietary tryptophan in various organs,
including the pineal gland and the retina. In the pineal gland, melatonin is produced at night …

Effect of melatonin supplementation on oxidative stress parameters: A systematic review and meta-analysis

M Morvaridzadeh, E Sadeghi, S Agah… - Pharmacological …, 2020 - Elsevier
Background Oxidative stress, defined as an imbalance between pro-oxidants and
neutralizing antioxidants within the body, is a growing public health concern. Oxidative …

[HTML][HTML] Antioxidants and pentoxifylline as coadjuvant measures to standard therapy to improve prognosis of patients with pneumonia by COVID-19

AP Chavarría, RRV Vázquez, JGD Cherit… - Computational and …, 2021 - Elsevier
The type 2 coronavirus causes severe acute respiratory syndrome (SARS-CoV-2) and
produces pneumonia with pulmonary alveolar collapse. In some cases it also causes sepsis …

Melatonin and vascular function

L Mendes, M Queiroz, CM Sena - Antioxidants, 2024 - mdpi.com
The indolamine hormone melatonin, also known as N-acetyl-5-methoxytrypamine, is
frequently associated with circadian rhythm regulation. Light can suppress melatonin …

Melatonin supplementation and the effects on clinical and metabolic status in Parkinson's disease: a randomized, double-blind, placebo-controlled trial

RD Kakhaki, V Ostadmohammadi, E Kouchaki… - Clinical neurology and …, 2020 - Elsevier
Objective This study was performed to evaluate the impact of melatonin supplementation on
clinical and metabolic profiles in people with Parkinson's disease (PD). Methods This …