Opinion statement Fluoropyrimidine (FP) is used to treat a wide range of cancers; however, it
is associated with drug-induced vascular toxicity, as well as angina pectoris and coronary …

Significance: Antineoplastic therapies have significantly improved the prognosis of oncology
patients. However, these treatments can bring to a higher incidence of side-effects, including …

Abstract Fluoropyrimidines—5-fluorouracil (5-FU) and capecitabine—have been implicated
as cardiotoxic chemotherapy agents. This rare, albeit potentially serious toxicity has been …

Cancer patients have an increased risk of cardiovascular disease and, notably, a significant
prevalence of acute coronary syndrome (ACS). It has been shown that an elevated presence …

Nanoparticles (NPs) have gained recognition for diagnosis, drug delivery, and therapy in
fatal diseases. This review focuses on the benefits of green synthesis of bioinspired NPs …

Aim We investigated the ability of baicalein (BAI) to enhance the anticancer potential of
capecitabine (CAP) in the MCF-7 cell line and its protective effect on CAP-induced …

Background Physical activity may increase the risk of cardiotoxicity (myocardial ischemia,
major arrhythmias) of 5-Fluorouracil, but this risk has never been investigated for its prodrug …

Background: Paracetamol (PCM) overdosing induces hepatotoxicity, which can result in
death if the dose is high enough and the patients are not given N-acetyl cysteine. Berberine …

Introduction 5-Fluorouracil (5-FU) is a chemotherapeutic agent used to treat various types of
cancers. Although widely used, it has consistently been attributed to cardiotoxicities after …

Objective To describe a possible case of capecitabine-induced myopericarditis in a patient
at the Cardio-Oncology Clinic in Calgary, AB. Design A literature search and adverse drug …