Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …

The neurotrophins are a family of proteins that are essential for the development of the
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …

Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …

Neurotrophins use two types of receptors, the Trk tyrosine kinase receptors and the p75
neurotrophin receptor (p75NTR), to regulate the growth, development, survival and repair of …

The'neurotrophin hypothesis of depression'is based largely on correlations between stress
or antidepressant treatment and down-or upregulation, respectively, of brain-derived …

Neurons are specialized cells with a complex morphology that represent the functional unit
of the nervous system. They are generated in remarkable numbers, particularly in higher …

The brain‐derived neurotrophic factor, BDNF, was discovered more than 30 years ago and,
like other members of the neurotrophin family, this neuropeptide is synthetized as a …

The neurotrophins are growth factors that play critical roles in the development,
maintenance, survival, and death of the nervous system. The signal transducing systems …

Depression and suicidal behavior have recently been shown to be associated with
disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) …