The regulatory roles of non-coding RNAs in angiogenesis and neovascularization from an epigenetic perspective

IA Hernández-Romero, L Guerra-Calderas… - Frontiers in …, 2019 - frontiersin.org
Angiogenesis is a crucial process for organ morphogenesis and growth during
development, and it is especially relevant during the repair of wounded tissue in adults. It is …

Noncoding RNAs databases: current status and trends

V Maracaja-Coutinho, AR Paschoal… - … biology of non-coding …, 2019 - Springer
One of the most important resources for researchers of noncoding RNAs is the information
available in public databases spread over the internet. However, the effective exploration of …

[HTML][HTML] Sperm microRNA pairs: new perspectives in the search for male fertility biomarkers

C Corral-Vazquez, A Salas-Huetos, J Blanco, F Vidal… - Fertility and …, 2019 - Elsevier
Objective To identify candidates of fertility biomarkers among pairs of human sperm
microRNAs. Design Expression data of 736 sperm microRNAs from fertile and infertile …

maTE: discovering expressed interactions between microRNAs and their targets

M Yousef, L Abdallah, J Allmer - Bioinformatics, 2019 - academic.oup.com
Motivation Disease is often manifested via changes in transcript and protein abundance.
MicroRNAs (miRNAs) are instrumental in regulating protein abundance and may …

miRNA expression profiles in isolated ventricular cardiomyocytes: Insights into doxorubicin-induced cardiotoxicity

Y Domínguez Romero, G Montoya Ortiz… - International journal of …, 2024 - mdpi.com
Doxorubicin (DOX), widely used as a chemotherapeutic agent for various cancers, is limited
in its clinical utility by its cardiotoxic effects. Despite its widespread use, the precise …

Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating …

G Silvestri, R Trotta, L Stramucci, JJ Ellis… - Blood cancer …, 2020 - aacrjournals.org
Persistence of drug-resistant quiescent leukemic stem cells (LSC) and impaired natural killer
(NK) cell immune response account for relapse of chronic myelogenous leukemia (CML) …

Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging

JC Russell, TK Kim, A Noori, GE Merrihew, JE Robbins… - GeroScience, 2020 - Springer
The nematode Caenorhabditis elegans has been instrumental in the identification of
evolutionarily conserved mechanisms of aging. C. elegans also has recently been found to …

Computational resources for prediction and analysis of functional miRNA and their targetome

I Monga, M Kumar - Computational Biology of Non-Coding RNA: Methods …, 2019 - Springer
Abstract microRNAs are evolutionarily conserved, endogenously produced, noncoding
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …

Human bone marrow mesenchymal stem cells-derived exosomes attenuated prostate cancer progression via the miR-99b-5p/IGF1R axis

S Jiang, H Chen, K He, J Wang - Bioengineered, 2022 - Taylor & Francis
ABSTRACT MicroRNA-99b-5p (miR-99b-5p) has been shown to be enriched in serum
exosomes of prostate cancer (PCa) patients treated with radiotherapy, while its function in …

Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

AI Youssef, GM Khaled, A Amleh - BMC cancer, 2023 - Springer
Background There is considerable evidence that microRNAs (miRNAs) regulate several key
tumor-associated genes/pathways and may themselves have a dual regulatory function …