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Improving drug delivery to solid tumors: priming the tumor microenvironment
IA Khawar, JH Kim, HJ Kuh - Journal of Controlled Release, 2015 - Elsevier
Malignant transformation and growth of the tumor mass tend to induce changes in the
surrounding microenvironment. Abnormality of the tumor microenvironment provides a …
surrounding microenvironment. Abnormality of the tumor microenvironment provides a …
The bioactivity and toxicological actions of carvacrol
ZE Suntres, J Coccimiglio, M Alipour - Critical reviews in food …, 2015 - Taylor & Francis
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants,
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …
Comparative statistical analysis of the release kinetics models for nanoprecipitated drug delivery systems based on poly (lactic-co-glycolic acid)
Poly (lactic-co-glycolic acid) is one of the most used polymers for drug delivery systems
(DDSs). It shows excellent biocompatibility, biodegradability, and allows spatio-temporal …
(DDSs). It shows excellent biocompatibility, biodegradability, and allows spatio-temporal …
PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems
A Ghaffarizadeh, R Heiland, SH Friedman… - PLoS computational …, 2018 - journals.plos.org
Many multicellular systems problems can only be understood by studying how cells move,
grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many …
grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many …
Perfluorooctanoic acid (PFOA) exposures and incident cancers among adults living near a chemical plant
V Barry, A Winquist, K Steenland - Environmental health …, 2013 - ehp.niehs.nih.gov
Background: Perfluorooctanoic acid (PFOA) is a synthetic chemical ubiquitous in the serum
of US residents. It causes liver, testicular, and pancreatic tumors in rats. Human studies are …
of US residents. It causes liver, testicular, and pancreatic tumors in rats. Human studies are …
Analysis on the current status of targeted drug delivery to tumors
Targeted drug delivery to tumor sites is one of the ultimate goals in drug delivery. Recent
progress in nanoparticle engineering has certainly improved drug targeting, but the results …
progress in nanoparticle engineering has certainly improved drug targeting, but the results …
The research and applications of quantum dots as nano-carriers for targeted drug delivery and cancer therapy
MX Zhao, BJ Zhu - Nanoscale Research Letters, 2016 - Springer
Abstract Quantum dots (QDs), nano-carriers for drugs, can help realize the targeting of
drugs, and improve the bioavailability of drugs in biological fields. And, a QD nano-carrier …
drugs, and improve the bioavailability of drugs in biological fields. And, a QD nano-carrier …
An insight to brain targeting utilizing polymeric nanoparticles: effective treatment modalities for neurological disorders and brain tumor
The delivery of therapeutic molecules to the brain remains an unsolved problem to the
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …
Intelligent nanomaterials for medicine: carrier platforms and targeting strategies in the context of clinical application
Nanomedical approaches are a major transforming factor in medical diagnosis and
therapies. Based on important earlier work in the field of liposomal drug delivery and …
therapies. Based on important earlier work in the field of liposomal drug delivery and …
The wound healing, chronic fibrosis, and cancer progression triad
B Rybinski, J Franco-Barraza… - Physiological …, 2014 - journals.physiology.org
For decades tumors have been recognized as “wounds that do not heal.” Besides the
commonalities that tumors and wounded tissues share, the process of wound healing also …
commonalities that tumors and wounded tissues share, the process of wound healing also …