Improving drug delivery to solid tumors: priming the tumor microenvironment

IA Khawar, JH Kim, HJ Kuh - Journal of Controlled Release, 2015 - Elsevier
Malignant transformation and growth of the tumor mass tend to induce changes in the
surrounding microenvironment. Abnormality of the tumor microenvironment provides a …

The bioactivity and toxicological actions of carvacrol

ZE Suntres, J Coccimiglio, M Alipour - Critical reviews in food …, 2015 - Taylor & Francis
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants,
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …

PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems

A Ghaffarizadeh, R Heiland, SH Friedman… - PLoS computational …, 2018 - journals.plos.org
Many multicellular systems problems can only be understood by studying how cells move,
grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many …

Perfluorooctanoic acid (PFOA) exposures and incident cancers among adults living near a chemical plant

V Barry, A Winquist, K Steenland - Environmental health …, 2013 - ehp.niehs.nih.gov
Background: Perfluorooctanoic acid (PFOA) is a synthetic chemical ubiquitous in the serum
of US residents. It causes liver, testicular, and pancreatic tumors in rats. Human studies are …

Analysis on the current status of targeted drug delivery to tumors

IK Kwon, SC Lee, B Han, K Park - Journal of Controlled Release, 2012 - Elsevier
Targeted drug delivery to tumor sites is one of the ultimate goals in drug delivery. Recent
progress in nanoparticle engineering has certainly improved drug targeting, but the results …

The research and applications of quantum dots as nano-carriers for targeted drug delivery and cancer therapy

MX Zhao, BJ Zhu - Nanoscale Research Letters, 2016 - Springer
Abstract Quantum dots (QDs), nano-carriers for drugs, can help realize the targeting of
drugs, and improve the bioavailability of drugs in biological fields. And, a QD nano-carrier …

An insight to brain targeting utilizing polymeric nanoparticles: effective treatment modalities for neurological disorders and brain tumor

Annu, A Sartaj, Z Qamar, S Md… - … in Bioengineering and …, 2022 - frontiersin.org
The delivery of therapeutic molecules to the brain remains an unsolved problem to the
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …

Intelligent nanomaterials for medicine: carrier platforms and targeting strategies in the context of clinical application

R Lehner, X Wang, S Marsch, P Hunziker - … : Nanotechnology, Biology and …, 2013 - Elsevier
Nanomedical approaches are a major transforming factor in medical diagnosis and
therapies. Based on important earlier work in the field of liposomal drug delivery and …

The wound healing, chronic fibrosis, and cancer progression triad

B Rybinski, J Franco-Barraza… - Physiological …, 2014 - journals.physiology.org
For decades tumors have been recognized as “wounds that do not heal.” Besides the
commonalities that tumors and wounded tissues share, the process of wound healing also …