Contribution of platelets to tumour metastasis

LJ Gay, B Felding-Habermann - Nature Reviews Cancer, 2011 - nature.com
Extensive experimental evidence shows that platelets support tumour metastasis. The
activation of platelets and the coagulation system have a crucial role in the progression of …

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

CSD Roxburgh, DC McMillan - Future oncology, 2010 - Taylor & Francis
Disease progression in cancer is dependent on the complex interaction between the tumor
and the host inflammatory response. There is substantial evidence in advanced cancer that …

Prognostic factors and predictive models in renal cell carcinoma: a contemporary review

M Sun, SF Shariat, C Cheng, V Ficarra, M Murai… - European urology, 2011 - Elsevier
CONTEXT: The natural history of renal cell carcinoma (RCC) is highly unpredictable. Small
renal masses may be accompanied by metastatic disease. Conversely, patients with locally …

Analysis of platelet count and new cancer diagnosis over a 10-year period

V Giannakeas, J Kotsopoulos, MC Cheung… - JAMA network …, 2022 - jamanetwork.com
Importance Individuals with cancer often have an elevated platelet count at the time of
diagnosis. The extent to which an elevated platelet count is an indicator of cancer is unclear …

Platelet CLEC2-podoplanin axis as a promising target for oral cancer treatment

BO Hwang, SY Park, ES Cho, X Zhang, SK Lee… - Frontiers in …, 2021 - frontiersin.org
Cancer tissues are not just simple masses of malignant cells, but rather complex and
heterogeneous collections of cellular and even non-cellular components, such as …

Paraneoplastic thrombocytosis: the secrets of tumor self-promotion

RJ Lin, V Afshar-Kharghan… - Blood, The Journal of the …, 2014 - ashpublications.org
Paraneoplastic thrombocytosis is associated with many solid tumors and often correlates
with reduced survival. Recent studies suggest that a pathogenic feed back loop may be …

The BRAF Mutation Is Predictive of Aggressive Clinicopathological Characteristics in Papillary Thyroid Microcarcinoma

KL Lin, OC Wang, XH Zhang, XX Dai, XQ Hu… - Annals of surgical …, 2010 - Springer
Background This study analyzed the utility of BRAF mutation screening of ultrasonography-
guided fine-needle aspiration biopsy (FNAB) specimens for predicting aggressive …

Predictors of response to radioligand therapy of metastatic castrate-resistant prostate cancer with 177Lu-PSMA-617

J Ferdinandus, E Eppard, FC Gaertner… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Radioligand therapy (RLT) with 177Lu-PSMA-617 (PSMA is prostate-specific membrane
antigen) is a novel targeted therapy for metastatic prostate cancer. In this study, we …

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and platelet count as predictors of long-term outcome after R0 resection for colorectal cancer

C Pedrazzani, G Mantovani, E Fernandes, F Bagante… - Scientific reports, 2017 - nature.com
Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count
(PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 …

Targeted Inhibition of lymphovascular invasion formation with creka peptide-modified silicasomes to boost chemotherapy in bladder cancer

Z Wu, B Li, Y Qie, S Wu, F Qi, T Chu, G Nie, H Hu - Nano Letters, 2024 - ACS Publications
Despite its significant clinical efficacy as a first-line treatment for advanced bladder cancer,
cisplatin-based chemotherapy provides a limited benefit for patients with lymphovascular …