Compared with primary tumor sites, metastatic sites appear more resistant to treatments and
respond differently to the treatment regimen. It may be due to the heterogeneity in the …

The present study explored the impact of inhibiting α (1, 6) fucosylation (core fucosylation)
on the functional phenotype of a cellular model of colorectal cancer (CRC) malignization …

Colorectal cancer (CRC) is one of the most dangerous types of malignant tumors, and
cancer metastasis is a major factor in the failure of CRC therapy. Recently, LOXL2 (lysyl …

Simple Summary Radiation-based anticancer therapies are often ineffective as cancer cells
may acquire radioresistance. Moreover, such therapies can cause unwanted side effects …

The survival rates in colon cancer patients are inversely proportional to the number of lymph
node metastases. The hypoxia-induced Epithelial to Mesenchymal Transition (EMT), driven …

Long-term survivors of glioblastoma multiforme (GBM) are at high risk of develo** second
primary neoplasms, including leukemia. For these patients, the use of classic tyrosine kinase …

Enhancing the effectiveness of colorectal cancer treatment is highly desirable. Radiation-
based anticancer therapy—such as proton therapy (PT)—can be used to shrink tumors …

Abstract Background/Objectives: The progression of colorectal cancer through clinically and
histopathologically well-defined stages is driven by specific mutations that activate …

Polysulfanes show chemopreventive effects against gastrointestinal tumors. We identified
diallyl tetrasulfide and its derivative, dibenzyl tetrasulfide (DBTTS), to be mitotic inhibitors …

The modular synthesis of the guanidine core by guanylation reactions using commercially
available ZnEt2 as a catalyst has been exploited as a tool for the rapid development of …