Tryptophan metabolism in health and disease
C Xue, G Li, Q Zheng, X Gu, Q Shi, Y Su, Q Chu… - Cell Metabolism, 2023 - cell.com
Tryptophan (Trp) metabolism primarily involves the kynurenine, 5-hydroxytryptamine, and
indole pathways. A variety of bioactive compounds produced via Trp metabolism can …
indole pathways. A variety of bioactive compounds produced via Trp metabolism can …
Advances in pathogenesis and therapeutic strategies for osteoporosis
S Song, Y Guo, Y Yang, D Fu - Pharmacology & therapeutics, 2022 - Elsevier
Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …
The role of the gut microbiota in the relationship between diet and human health
The interplay between diet, the gut microbiome, and host health is complex. Diets
associated with health have many similarities: high fiber, unsaturated fatty acids, and …
associated with health have many similarities: high fiber, unsaturated fatty acids, and …
Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders
Y Chen, J Xu, Y Chen - Nutrients, 2021 - mdpi.com
Emerging evidence indicates that gut microbiota is important in the regulation of brain
activity and cognitive functions. Microbes mediate communication among the metabolic …
activity and cognitive functions. Microbes mediate communication among the metabolic …
Gut microbial molecules in behavioural and neurodegenerative conditions
BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
[HTML][HTML] Osteoporosis: Pathophysiology and therapeutic options
U Föger-Samwald, P Dovjak, U Azizi-Semrad… - EXCLI …, 2020 - ncbi.nlm.nih.gov
Osteoporosis is a metabolic bone disease that, on a cellular level, results from osteoclastic
bone resorption not compensated by osteoblastic bone formation. This causes bones to …
bone resorption not compensated by osteoblastic bone formation. This causes bones to …
[HTML][HTML] Mouse microbiota models: comparing germ-free mice and antibiotics treatment as tools for modifying gut bacteria
As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …
physiologic homeostasis and also as a modulator of disease processes, there has been a …
Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut
The gut microbiota regulates levels of serotonin (5-hydroxytryptamine (5-HT)) in the
intestinal epithelium and lumen,,,–. However, whether 5-HT plays a functional role in …
intestinal epithelium and lumen,,,–. However, whether 5-HT plays a functional role in …
Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
Microbial metabolites are known to modulate immune responses of the host. The main
metabolites derived from microbial fermentation of dietary fibers in the intestine, short-chain …
metabolites derived from microbial fermentation of dietary fibers in the intestine, short-chain …
Neuromicrobiology, an emerging neurometabolic facet of the gut microbiome?
The concept of the gut microbiome is emerging as a metabolic interactome influenced by
diet, xenobiotics, genetics, and other environmental factors that affect the host's absorption …
diet, xenobiotics, genetics, and other environmental factors that affect the host's absorption …